tert-Butyl+cyclopropanecarboxylate
Artikel-Nr:
(BOSSBS-8037R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8037R-A647
Lokale Artikelnummer::
BOSSBS-8037R-A647
Beschreibung:
COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. Down-regulates activation of NF-kappa-B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8551R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8551R-A680
Lokale Artikelnummer::
BOSSBS-8551R-A680
Beschreibung:
Nitrotyrosine is a marker for inflammation and nitric oxide (NO) production and is formed in the presence of the active metabolite NO. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage <i>in vivo</i>. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques and chronic renal failure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7750R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7750R-A555
Lokale Artikelnummer::
BOSSBS-7750R-A555
Beschreibung:
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4061R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4061R-A350
Lokale Artikelnummer::
BOSSBS-4061R-A350
Beschreibung:
The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8551R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8551R-A750
Lokale Artikelnummer::
BOSSBS-8551R-A750
Beschreibung:
Nitrotyrosine is a marker for inflammation and nitric oxide (NO) production and is formed in the presence of the active metabolite NO. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage in vivo. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques and chronic renal failure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3648R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3648R-A647
Lokale Artikelnummer::
BOSSBS-3648R-A647
Beschreibung:
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7750R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7750R-A488
Lokale Artikelnummer::
BOSSBS-7750R-A488
Beschreibung:
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13249R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13249R-A647
Lokale Artikelnummer::
BOSSBS-13249R-A647
Beschreibung:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1460R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1460R-A647
Lokale Artikelnummer::
BOSSBS-1460R-A647
Beschreibung:
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13249R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13249R-A555
Lokale Artikelnummer::
BOSSBS-13249R-A555
Beschreibung:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7725R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7725R-A750
Lokale Artikelnummer::
BOSSBS-7725R-A750
Beschreibung:
Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7851R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7851R-CY5.5
Lokale Artikelnummer::
BOSSBS-7851R-CY5.5
Beschreibung:
Microtubules, polymers of alpha and beta tubulin subunits,form the mitotic spindle of a dividing cell and help to organizemembranous organelles during interphase. Katanin is a heterodimerthat consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDaaccessory protein (p80 subunit B 1). The p60 subunit acts to severand disassemble microtubules, while the p80 subunit targets theenzyme to the centrosome. Katanin is a member of the AAA family ofATPases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4131R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4131R-CY7
Lokale Artikelnummer::
BOSSBS-4131R-CY7
Beschreibung:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9243R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9243R-CY5
Lokale Artikelnummer::
BOSSBS-9243R-CY5
Beschreibung:
RNF20 is an E3 ubiquitin ligase protein that mediates monoubiquitination of histone H2B and the methylation of histone H3. It forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. It is required for transcriptional activation of Hox genes. It is recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5328R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5328R-A488
Lokale Artikelnummer::
BOSSBS-5328R-A488
Beschreibung:
HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1319R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1319R-A680
Lokale Artikelnummer::
BOSSBS-1319R-A680
Beschreibung:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
VE:
1 * 100 µl
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