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2-Amino-4-chloro-7-methoxyquinazoline
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2-Amino-4-chloro-7-methoxyquinazoline
Artikel-Nr:
(BOSSBS-13447R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13447R-A750
Lokale Artikelnummer::
BOSSBS-13447R-A750
Beschreibung:
Glycogen synthesis is initiated by the autoglucosylation of Glycogenin-1. Specifically, Glycogenin-1 glucosylates itself to begin the synthesis of glycogen in mammalian skeletal muscle. It acts as the primer to which further glucose monomers may be added. All of the Glycogenin-1 molecules contain at least one glucosyl residue before autoglucosylation begins. The first step of the glycogen synthesis occurs when a glucose molecule from UDP-glucose binds to the hydroxyl group of Tyr 194 on the Glycogenin-1 molecule. Using its glucosyltransferase activity, Glycogenin-1 adds more glucoses, each one coming from UDP-glucose. The glycosylation process reaches a plateau when five new glucose residues have been added, at which point glycogen synthase (GS) takes over and further elongates the chain. Glycogenin-1 remains covalently attached to the reducing end of the glycogen molecule.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12124R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12124R-A350
Lokale Artikelnummer::
BOSSBS-12124R-A350
Beschreibung:
The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients. PROT (Sodium-dependent proline transporter), also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain. PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals. Enriched in glutamatergic synaptic terminals, it is likely that PROT plays an important role in excitatory events of neurotransmission. PROT-mediated proline uptake is inhibited by compounds such as benztropine, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL). These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5343R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5343R-A488
Lokale Artikelnummer::
BOSSBS-5343R-A488
Beschreibung:
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5342R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5342R-FITC
Lokale Artikelnummer::
BOSSBS-5342R-FITC
Beschreibung:
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13093R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13093R-A350
Lokale Artikelnummer::
BOSSBS-13093R-A350
Beschreibung:
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13094R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13094R-A647
Lokale Artikelnummer::
BOSSBS-13094R-A647
Beschreibung:
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(ABNOH00007299-D01)
Lieferant:
Abnova
Hersteller-Artikelnummer::
H00007299-D01
Lokale Artikelnummer::
ABNOH00007299-D01
Beschreibung:
Anti-TYR Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BACE4000627.0001)
Lieferant:
BACHEM BIOCHEMICA
Hersteller-Artikelnummer::
4000627.0001
Lokale Artikelnummer::
BACE4000627.0001
Beschreibung:
H-Gly-Tyr-Gly-OH
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-3016R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3016R-HRP
Lokale Artikelnummer::
BOSSBS-3016R-HRP
Beschreibung:
p44/42 MAP Kinase(Thr202); ERK (extracellular signal regulated kinase), also known as MAPK (mitogen activated protein kinase) has two closely related isoforms of 44 kDa and 42 kDa, respectively. These kinases belong to a family of serine/threonine kinases that are activated upon treatment of cells with a large variety of stimuli including mitogens, hormones, growth factors, cytokines, and bioactive peptides. Cell stimulation induces the activation of a signaling cascade, the downstream effects of which have been linked to the regulation of cell growth and differentiation as well as the cytoskeleton. ERK1 and ERK2 are phosphorylated within the activation loop on both a Threonine and a Tyrosine residue (within a Thr-Glu-Tyr motif) by MEKs (MAPK/ERK kinases), thereby greatly elevating the activity of ERK1&2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12124R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12124R-CY3
Lokale Artikelnummer::
BOSSBS-12124R-CY3
Beschreibung:
The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients. PROT (Sodium-dependent proline transporter), also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain. PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals. Enriched in glutamatergic synaptic terminals, it is likely that PROT plays an important role in excitatory events of neurotransmission. PROT-mediated proline uptake is inhibited by compounds such as benztropine, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL). These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BACE4015938.0001)
Lieferant:
BACHEM BIOCHEMICA
Hersteller-Artikelnummer::
4015938.0001
Lokale Artikelnummer::
BACE4015938.0001
Beschreibung:
The oxytocin antagonist OVTA shows enhanced affinity for rat uterine oxytocin receptors after iodination.
VE:
1 * 1 mg
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ICNA03FK01001)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
03FK01001
Lokale Artikelnummer::
ICNA03FK01001
Beschreibung:
Z-Asp(Ome)-Glu(Ome)-Val-Asp(Ome)-fluoromethylketone
VE:
1 * 1 mg
Artikel-Nr:
(ORIGTA323679)
Lieferant:
OriGene
Hersteller-Artikelnummer::
TA323679
Lokale Artikelnummer::
ORIGTA323679
Beschreibung:
Anti-TYR Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9356R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9356R-CY5.5
Lokale Artikelnummer::
BOSSBS-9356R-CY5.5
Beschreibung:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9356R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9356R-CY5
Lokale Artikelnummer::
BOSSBS-9356R-CY5
Beschreibung:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9356R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9356R-CY3
Lokale Artikelnummer::
BOSSBS-9356R-CY3
Beschreibung:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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