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2-Amino-5-bromo-4-methoxybenzoic+acid
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2-Amino-5-bromo-4-methoxybenzoic+acid
Artikel-Nr:
(BOSSBS-8436R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8436R-CY3
Lokale Artikelnummer::
BOSSBS-8436R-CY3
Beschreibung:
BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5833R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5833R-A750
Lokale Artikelnummer::
BOSSBS-5833R-A750
Beschreibung:
This gene encodes a member of the "fused gene" family of proteins, which contain N terminus EF hand domains and multiple tandem peptide repeats. The encoded protein contains two EF hand Ca2+ binding domains in its N terminus and two glutamine and threonine rich 60 amino acid repeats in its C terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12423R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12423R-CY5
Lokale Artikelnummer::
BOSSBS-12423R-CY5
Beschreibung:
Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic β-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15420R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15420R-A750
Lokale Artikelnummer::
BOSSBS-15420R-A750
Beschreibung:
HBS1L is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and _-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9372R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9372R-A555
Lokale Artikelnummer::
BOSSBS-9372R-A555
Beschreibung:
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12423R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12423R-CY7
Lokale Artikelnummer::
BOSSBS-12423R-CY7
Beschreibung:
Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic β-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9372R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9372R-A750
Lokale Artikelnummer::
BOSSBS-9372R-A750
Beschreibung:
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarised by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
Artikel-Nr:
(BOSSBS-11497R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11497R-CY7
Lokale Artikelnummer::
BOSSBS-11497R-CY7
Beschreibung:
VAX2 is a 290 amino acid homeobox protein that plays a crucial role in development of the eye, particularly in the specification of the ventral optic vesicle and in establishment of a correct dorsoventral pattern. VAX2 acts as a transcription factor with VAX1 to cooperatively regulate retinal differentiation, neuroepithelial cell proliferation and axial polarization in the retina. Together, VAX1 and VAX2 repress transcription of Pax-6, a strong inducer of retinal development. VAX1 and VAX2 localize to the nucleus and contain one homeobox DNA-binding domain each.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9676R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9676R-HRP
Lokale Artikelnummer::
BOSSBS-9676R-HRP
Beschreibung:
MIC1 is a 657 amino acid protein that contains one MIC1 domain and is encoded by a gene which maps to human chromosome 18. Chromosome 18 houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0202R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0202R-CY5
Lokale Artikelnummer::
BOSSBS-0202R-CY5
Beschreibung:
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9909R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9909R-A750
Lokale Artikelnummer::
BOSSBS-9909R-A750
Beschreibung:
GGT6 belongs to the gamma-glutamyltransferase family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis. GGT6 has very limited amino acid similarity to GGT1 and it's enzymatic activities are currently uncharacterised. GGT assays are of current widespread clinical use to help assess tissue damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9372R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9372R-A647
Lokale Artikelnummer::
BOSSBS-9372R-A647
Beschreibung:
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11497R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11497R-A350
Lokale Artikelnummer::
BOSSBS-11497R-A350
Beschreibung:
VAX2 is a 290 amino acid homeobox protein that plays a crucial role in development of the eye, particularly in the specification of the ventral optic vesicle and in establishment of a correct dorsoventral pattern. VAX2 acts as a transcription factor with VAX1 to cooperatively regulate retinal differentiation, neuroepithelial cell proliferation and axial polarization in the retina. Together, VAX1 and VAX2 repress transcription of Pax-6, a strong inducer of retinal development. VAX1 and VAX2 localize to the nucleus and contain one homeobox DNA-binding domain each.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9676R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9676R-A647
Lokale Artikelnummer::
BOSSBS-9676R-A647
Beschreibung:
MIC1 is a 657 amino acid protein that contains one MIC1 domain and is encoded by a gene which maps to human chromosome 18. Chromosome 18 houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15483R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15483R-HRP
Lokale Artikelnummer::
BOSSBS-15483R-HRP
Beschreibung:
HIBADH is a 336 amino acid mitochondrial enzyme that catalyses the NAD+-dependent, reversible oxidisation of 3-Hydroxyisobutyrate to methylmalonate semialdehyde, an intermediate of valine catabolism. The enzyme functions as a homodimer between a pH of 7,0 and 10,0, with optimal activity between 8,8 and 9,0. It was previously hypothesised that defects in the gene encoding HIBADH may be the cause of 3-Hydroxyisobutyric aciduria, a rare disorder that is characterised by a variety of clinical manifestations such as neurodevelopmental problems and dysmorphic features. However, it was shown that HIBADH activity was equal in patients with 3-Hydroxyisobutyric aciduria as compared with controls.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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