2-Brom-4,5-dimethoxybenzoes\\\\\\\\u00E4ure
Artikel-Nr:
(BOSSBS-12946R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12946R-FITC
Lokale Artikelnummer::
BOSSBS-12946R-FITC
Beschreibung:
CRP2 is a 193 amino acid nuclear protein that belongs to the CRP family of LIM domain proteins. Highly expressed in smooth muscle of aorta, CRP2 is thought to have a role in embryonic vascular system development and is downregulated following cell injury or PDGF-B exposure. CRP2 contains two LIM zinc-binding domains and is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12163R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12163R-A680
Lokale Artikelnummer::
BOSSBS-12163R-A680
Beschreibung:
CAPS2 is a 557 amino acid calcium-binding protein that is abundantly expressed, with highest expression found in placenta, testis, colon, lung and brain. CAPS2 contains three EF-hand domains and exists as three alternatively spliced isoforms. Suggested to play a role in large dense-core vesicle (LDCV) exocytosis, CAPS2 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3460R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3460R-CY5.5
Lokale Artikelnummer::
BOSSBS-3460R-CY5.5
Beschreibung:
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12144R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12144R
Lokale Artikelnummer::
BOSSBS-12144R
Beschreibung:
Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1). Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2,3). Human Sck transcripts are present at high levels in liver, pancreas, prostate and ovary (4,5). In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6). Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7,8).
VE:
1 * 100 µl
Artikel-Nr:
(COBBBB-3094-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
BB-3094-1G
Lokale Artikelnummer::
COBBBB-3094-1G
Beschreibung:
3-((4,5-Dihydrothiazol-2-yl)carbamoyl)phenylboronsäure
VE:
1 * 1 g
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Artikel-Nr:
(PROOCIL-PCB-177-C)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-177-C
Lokale Artikelnummer::
PROOCIL-PCB-177-C
Beschreibung:
2,2',3,3',4,5',6'-Heptachlorbiphenyl (PCB Nr. 177)
VE:
1 * 5 mg
Artikel-Nr:
(BOSSBS-9769R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9769R-A680
Lokale Artikelnummer::
BOSSBS-9769R-A680
Beschreibung:
C10orf62 is a 223 amino acid protein encoded by a gene that maps to human chromosome 10q24.1. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6471R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6471R-A488
Lokale Artikelnummer::
BOSSBS-6471R-A488
Beschreibung:
Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12411R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12411R-FITC
Lokale Artikelnummer::
BOSSBS-12411R-FITC
Beschreibung:
Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12411R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12411R-CY7
Lokale Artikelnummer::
BOSSBS-12411R-CY7
Beschreibung:
Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6471R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6471R-A647
Lokale Artikelnummer::
BOSSBS-6471R-A647
Beschreibung:
Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9716R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9716R-A750
Lokale Artikelnummer::
BOSSBS-9716R-A750
Beschreibung:
Chromosome 10 contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumour suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterised by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. The KIAA1279 gene product has been provisionally designated KIAA1279 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11589R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11589R-CY3
Lokale Artikelnummer::
BOSSBS-11589R-CY3
Beschreibung:
The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxC5 is a 222 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Existing as multiple alternatively spliced isoforms, HoxC5 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. The gene encoding HoxC5 maps to a cluster of Hox proteins on chromosome 12 that are essential for morphogenesis. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9448R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9448R-CY5.5
Lokale Artikelnummer::
BOSSBS-9448R-CY5.5
Beschreibung:
The tetraspanin family is a group of cell surface proteins that regulate cell development, activation, growth and motility. Each member contains four hydrophobic domains and participates in the mediation of signal transduction. NET-5, also known as TSPAN9 (tetraspanin 9), is a 239 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. NET-5 forms a complex with GPVI in the tetraspanin microdomains on the platelet surface, and is encoded by a gene that maps to human chromosome 12p13.33. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
VE:
1 * 100 µl
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazoliumbromid, Sigma-Aldrich®
Artikel-Nr:
(PROOCIL-PCB-161-C)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-161-C
Lokale Artikelnummer::
PROOCIL-PCB-161-C
Beschreibung:
2,3,3',4,5',6-Hexachlorbiphenyl (PCB Nr. 161)
VE:
1 * 5 mg
Preis auf Anfrage
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