2-Brom-4,5-dimethoxybenzoes\u00E4ure
Artikel-Nr:
(BOSSBS-13247R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13247R-A350
Lokale Artikelnummer::
BOSSBS-13247R-A350
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G Alpha subunits have been identified; these include G Alpha s, G Alpha i, G Alpha q and G Alpha 12/13. The two members of the fourth class of G Alpha subunit proteins, G Alpha 12 and G Alpha 13, are insensitive to ADP-ribosylation by pertussis toxin, share 67% identity with each other and less than 45% identity with other G Alpha subunits and are widely expressed in a broad range of tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13247R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13247R-A647
Lokale Artikelnummer::
BOSSBS-13247R-A647
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G Alpha subunits have been identified; these include G Alpha s, G Alpha i, G Alpha q and G Alpha 12/13. The two members of the fourth class of G Alpha subunit proteins, G Alpha 12 and G Alpha 13, are insensitive to ADP-ribosylation by pertussis toxin, share 67% identity with each other and less than 45% identity with other G Alpha subunits and are widely expressed in a broad range of tissues.
VE:
1 * 100 µl
Artikel-Nr:
(ENAMEN30008974.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN30008974.1G
Lokale Artikelnummer::
ENAMEN30008974.1G
Beschreibung:
1-Chlorphthalazin
VE:
1 * 1 g
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Lieferant:
Biotium
Beschreibung:
Recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
Artikel-Nr:
(BOSSBS-12321R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12321R-A750
Lokale Artikelnummer::
BOSSBS-12321R-A750
Beschreibung:
Tect3 is a 607 amino acid single-pass type I membrane protein that belongs to the tectonic family and exists as four alternatively spliced isoforms. Tect3 interacts with MKS1 and may be involved in apoptosis regulation. The gene that encodes Tect3 contains approximately 31560 bases and maps to human chromosome 10q24.1. Spanning nearly 135 million base pairs and encoding nearly 1200 genes, chromosome 10 makes up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, Cockayne syndrome, multiple endocrine neoplasia type 2 and porphyria. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10.
VE:
1 * 100 µl
Lieferant:
FLUOROCHEM
Beschreibung:
2,3-Dichlorbenzoesäure
Artikel-Nr:
(E406-5ML)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRCE406-5ML
Beschreibung:
Ethidiumbromid in 0,625 mg/ml Tropfflasche. Ein Tropfen in 50 ml flüssiger Agarose oder Puffer verdünnt ergibt eine Endkonzentration von 0,5 μg/ml. In einer Konzentration von 0,5 μg/ml ist Ethidiumbromid zweckmäßig in Agarose- oder Acrylamidgelen für die Bandenfeststellung. Es ermöglicht die Detektion von Nukleinsäure in Mengen von lediglich 10 ng. In höheren Konzentrationen (0,5 - 1,0 μg/ml) kann es bei der Aufreinigung von DNA in einem Caesiumchlorid-Gradienten verwendet werden.
VE:
1 * 5 mL
Artikel-Nr:
(HECH40075010)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
40075010
Lokale Artikelnummer::
HECH40075010
Beschreibung:
Ion exchanger for purified water.
VE:
1 * 1 ST
Lieferant:
MACHEREY-NAGEL
Beschreibung:
Die passenden Schraubverschlüsse sind fertig montiert.
Artikel-Nr:
(FLUO020763-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
020763-1G
Lokale Artikelnummer::
FLUO020763-1G
Beschreibung:
3'-Cyanbiphenyl-4-carbonsäure
VE:
1 * 1 g
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Artikel-Nr:
(BSNCVDPRO1500BOA45)
Lieferant:
BASAN
Hersteller-Artikelnummer::
VDPRO1500BOA45
Lokale Artikelnummer::
BSNCVDPRO1500BOA45
Beschreibung:
Ultraleichte Mikrofaser, bequeme Passform durch nahtloses Schuhdesign, BOA® Fit System, Staubschutzzunge.
VE:
1 * 1 PAAR
Lieferant:
GERING
Beschreibung:
Alcohol meters with a standard temperature of 20 °C.
Artikel-Nr:
(MANA702181)
Lieferant:
MACHEREY-NAGEL
Hersteller-Artikelnummer::
702181
Lokale Artikelnummer::
MANA702181
Beschreibung:
The suitable screw closures have bonded septa.
VE:
1 * 100 ST
Lieferant:
Hach
Beschreibung:
Reagenzien für extern oder im Labor durchgeführte photometrische Analysen
Preis auf Anfrage
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