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Methyl-1H-imidazole-5-carboxylate
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Methyl-1H-imidazole-5-carboxylate
Artikel-Nr:
(BTIUBNUM0656-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0656-50
Lokale Artikelnummer::
BTIUBNUM0656-50
Beschreibung:
This MAb recognizes human 17-26 kDa protein, which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha). TNF-alpha can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
VE:
1 * 50 µl
Lieferant:
Biotium
Beschreibung:
This MAb recognizes human 17-26 kDa protein, which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha). TNF-alpha can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
Lieferant:
Sigma-Aldrich
Beschreibung:
1,7-Dimethylxanthin, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-1175R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1175R-CY5
Lokale Artikelnummer::
BOSSBS-1175R-CY5
Beschreibung:
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Appearance: Clear light yellow Viscous liquid
Artikel-Nr:
(BOSSBS-8131R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8131R-A647
Lokale Artikelnummer::
BOSSBS-8131R-A647
Beschreibung:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC42 (coiled-coil domain containing 42) is a 316 amino acid protein encoded by a gene that maps to human chromosome 17p13.1. Encoding over 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8131R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8131R-CY5
Lokale Artikelnummer::
BOSSBS-8131R-CY5
Beschreibung:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC42 (coiled-coil domain containing 42) is a 316 amino acid protein encoded by a gene that maps to human chromosome 17p13.1. Encoding over 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8131R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8131R-A680
Lokale Artikelnummer::
BOSSBS-8131R-A680
Beschreibung:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC42 (coiled-coil domain containing 42) is a 316 amino acid protein encoded by a gene that maps to human chromosome 17p13.1. Encoding over 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
N-Acetyl-β-D-glucosamin 98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-Chloro-6,6-dimethyl-2-hepten-4-yne 95%
Artikel-Nr:
(APOSOR26854-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR26854-100G
Lokale Artikelnummer::
APOSOR26854-100G
Beschreibung:
2,6-Dibrom-4-chloranilin 97%
VE:
1 * 100 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Dichloro-bis-(tricyclohexylphosphin)-palladium(II) 98%
Lieferant:
VWR Chemicals
Beschreibung:
Natriumthiosulfat Pentahydrat ≥98%, gereinigt
Artikel-Nr:
(BLDPBD206260-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD206260-250MG
Lokale Artikelnummer::
BLDPBD206260-250MG
Beschreibung:
1H-Benzoimidazole-5-carboxylic acid amide 95%
VE:
1 * 250 mg
Artikel-Nr:
(APOSPC28063-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC28063-1G
Lokale Artikelnummer::
APOSPC28063-1G
Beschreibung:
Ethyl 1-(3-fluorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylate, tech
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-0657R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0657R-CY5.5
Lokale Artikelnummer::
BOSSBS-0657R-CY5.5
Beschreibung:
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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