2-Chloro-3,4-difluoroaniline
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-Brom-2-chlor-5-nitrobenzol 98%
Artikel-Nr:
(BOSSBS-4278R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4278R-HRP
Lokale Artikelnummer::
BOSSBS-4278R-HRP
Beschreibung:
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4278R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4278R-CY5
Lokale Artikelnummer::
BOSSBS-4278R-CY5
Beschreibung:
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13642R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13642R-FITC
Lokale Artikelnummer::
BOSSBS-13642R-FITC
Beschreibung:
Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1,2). Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3,4). GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N-terminus (5,6). GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6). This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6,7). Moreover, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6).
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR510203-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR510203-1G
Lokale Artikelnummer::
APOSOR510203-1G
Beschreibung:
2-Chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one hydrochloride ≥98%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-9244R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9244R-CY5
Lokale Artikelnummer::
BOSSBS-9244R-CY5
Beschreibung:
Tripartite motif-containing protein 34 (TRIM34), also known as RING finger protein 21 (RNF21) or interferon-responsive finger protein 1 (IFP1), is a 488 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Three isoforms of TRIM34 exist as a result of alternative splicing events. Isoform 1, the most abundant isoform, is highly expressed in placenta, spleen, colon and peripheral blood leukocytes. Studies have shown that Interferon (IFN) stimulation leads to an upregulation of TRIM34. These findings suggest that TRIM34 maybe a downstream effector that mediates IFN activities.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11318R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11318R-CY3
Lokale Artikelnummer::
BOSSBS-11318R-CY3
Beschreibung:
The human ataxin-7 gene, also known as spinocerebellar ataxia 7 or SCA7, maps to chromosome 3p13-p12, has a 2,727-bp open reading frame, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1,2). SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product (3,4). Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5). Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6).
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD8392-100G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD8392-100G
Lokale Artikelnummer::
BLDPBD8392-100G
Beschreibung:
Ethyl-5-chlor-1H-indol-2-carboxylat 98%
VE:
1 * 100 g
Lieferant:
Thermo Scientific
Beschreibung:
2-Chlor-4,6-dimethoxy-1,3,5-triazin 98%
Artikel-Nr:
(76750-5ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
76750-5ML
Lokale Artikelnummer::
SUPL76750-5ML
Beschreibung:
Chlordimethyl(pentafluorphenyl)silan (Flophemesylchlorid), Supelco®
VE:
1 * 5 mL
Artikel-Nr:
(46747.03)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
46747.03
Lokale Artikelnummer::
ALFA46747.03
Beschreibung:
Allyl(chloro)[1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene]palladium(II)
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-4278R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4278R-A680
Lokale Artikelnummer::
BOSSBS-4278R-A680
Beschreibung:
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterised by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of foetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD22981-100G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD22981-100G
Lokale Artikelnummer::
BLDPBD22981-100G
Beschreibung:
2-Amino-4-chlor-5-methylbenzolsulfonsäure 97%
VE:
1 * 100 g
Lieferant:
Biotium
Beschreibung:
The epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Artikel-Nr:
(BOSSBS-4278R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4278R-A350
Lokale Artikelnummer::
BOSSBS-4278R-A350
Beschreibung:
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13642R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13642R-A750
Lokale Artikelnummer::
BOSSBS-13642R-A750
Beschreibung:
Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1,2). Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3,4). GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N-terminus (5,6). GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6). This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6,7). Moreover, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6).
VE:
1 * 100 µl
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