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(Methylsulphonyl)methanesulphonyl+chloride
Artikel-Nr:
(PRSIXP-5732-M)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5732-M
Lokale Artikelnummer::
PRSIXP-5732-M
Beschreibung:
Anti-CCL2 Mouse Monoclonal Antibody [clone: 2.2-4H5-01A11]
VE:
1 * 500 µG
Artikel-Nr:
(PROOCIL-PCB-196-CS)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-196-CS
Lokale Artikelnummer::
PROOCIL-PCB-196-CS
Beschreibung:
Organic Standard, 2,2',3,3',4,4',5,6'-Octachlorbiphenyl (PCB Nr. 196) 100 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1,2 mL
Artikel-Nr:
(BLEG571309)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
571309
Lokale Artikelnummer::
BLEG571309
Beschreibung:
ELISA Standard four pack contains four vials of recombinant human IL-22 at >5 ng per vial. Recommended for ELISA application only. Standards are calibrated against a BioLegend Master Calibrator.
VE:
1 * 1 Pack.
 This is a MarketSource item. Additional charges may apply
Lieferant:
Agilent
Beschreibung:
Clip, trap mounting, universal 22 - 25 mm Ext.Ø, Für: LC/MS
Artikel-Nr:
(BOSSBS-12495R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-CY7
Lokale Artikelnummer::
BOSSBS-12495R-CY7
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8594R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8594R-A555
Lokale Artikelnummer::
BOSSBS-8594R-A555
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12495R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-CY3
Lokale Artikelnummer::
BOSSBS-12495R-CY3
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12495R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-CY5
Lokale Artikelnummer::
BOSSBS-12495R-CY5
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-A680
Lokale Artikelnummer::
BOSSBS-13343R-A680
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(PROOCIL-PCB-42)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-42
Lokale Artikelnummer::
PROOCIL-PCB-42
Beschreibung:
Organic Standard, 2,2',3,4'-Tetrachlorbiphenyl (PCB Nr. 42) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(BLEG684902)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
684902
Lokale Artikelnummer::
BLEG684902
Beschreibung:
Anti-Cyclin D3 Mouse Monoclonal Antibody [clone: DCS-22]
VE:
1 * 100 µG
This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
Aminoacetaldehyddimethylacetal, Sigma-Aldrich®
Artikel-Nr:
(EHERC10655670)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C10655670
Lokale Artikelnummer::
EHERC10655670
Beschreibung:
4,4'-(1-Methylpropyliden)diphenol
VE:
1 * 100 mg
Artikel-Nr:
(PROOCIL-PCB-16)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-16
Lokale Artikelnummer::
PROOCIL-PCB-16
Beschreibung:
Organic Standard, 2,2',3-Trichlorbiphenyl (PCB Nr. 16) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-9174R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9174R-A488
Lokale Artikelnummer::
BOSSBS-9174R-A488
Beschreibung:
Tripartite motif-containing protein 3 (TRIM3), also known as RING finger protein 22 (RNF22), RING finger protein 97 (RNF97) or brain-expressed RING finger protein (BERP), is a 744 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Localized to cytoplasmic filaments, TRIM3 has been shown to interact with å-actinin-4 and myosin V, two proteins associated with the actin cytoskeleton. Specifically, å-actinin-4 interacts with the RBCC domain of TRIM3, and the C-terminal tail of Myosin V interacts with with the unique C-terminal ∫-propeller domain of TRIM3. These associations suggest that TRIM3 may play a role in cell motility and cargo transport. Three named isoforms of TRIM3 exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15318R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15318R-A350
Lokale Artikelnummer::
BOSSBS-15318R-A350
Beschreibung:
C9orf169 (chromosome 9 open reading frame 169) is a 423 amino acid single-pass membrane protein that belongs to the clpA/clpB family and torsin subfamily. The gene encoding C9orf169 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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