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3,5-Dibrom-2-chlorpyridin
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3,5-Dibrom-2-chlorpyridin
Artikel-Nr:
(BOSSBS-1726R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1726R-FITC
Lokale Artikelnummer::
BOSSBS-1726R-FITC
Beschreibung:
Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13141R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13141R-A750
Lokale Artikelnummer::
BOSSBS-13141R-A750
Beschreibung:
Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2972R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2972R-A555
Lokale Artikelnummer::
BOSSBS-2972R-A555
Beschreibung:
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13133R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13133R-CY5
Lokale Artikelnummer::
BOSSBS-13133R-CY5
Beschreibung:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2972R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2972R-CY5
Lokale Artikelnummer::
BOSSBS-2972R-CY5
Beschreibung:
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13133R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13133R-A680
Lokale Artikelnummer::
BOSSBS-13133R-A680
Beschreibung:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13133R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13133R-A647
Lokale Artikelnummer::
BOSSBS-13133R-A647
Beschreibung:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13133R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13133R-A555
Lokale Artikelnummer::
BOSSBS-13133R-A555
Beschreibung:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI92-374)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-374
Lokale Artikelnummer::
PRSI92-374
Beschreibung:
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
VE:
1 * 0,05 mg
Artikel-Nr:
(BOSSBS-13134R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13134R
Lokale Artikelnummer::
BOSSBS-13134R
Beschreibung:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Constituent of focal adhesions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5540R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5540R-CY5.5
Lokale Artikelnummer::
BOSSBS-5540R-CY5.5
Beschreibung:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Constituent of focal adhesions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1726R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1726R-A350
Lokale Artikelnummer::
BOSSBS-1726R-A350
Beschreibung:
Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1726R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1726R-A488
Lokale Artikelnummer::
BOSSBS-1726R-A488
Beschreibung:
Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2972R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2972R-FITC
Lokale Artikelnummer::
BOSSBS-2972R-FITC
Beschreibung:
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2972R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2972R-HRP
Lokale Artikelnummer::
BOSSBS-2972R-HRP
Beschreibung:
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2972R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2972R-A750
Lokale Artikelnummer::
BOSSBS-2972R-A750
Beschreibung:
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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