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3,5-Dichloro-4-fluorophenol
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3,5-Dichloro-4-fluorophenol
Artikel-Nr:
(BOSSBS-12460R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12460R
Lokale Artikelnummer::
BOSSBS-12460R
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
VE:
1 * 100 µl
Artikel-Nr:
(765-1089)
Lieferant:
MOLLER THERM
Hersteller-Artikelnummer::
106350
Lokale Artikelnummer::
MOLT106350
Beschreibung:
Room thermometer with five (340 mm) or seven (420 mm) balls.
VE:
1 * 1 ST
 This is a MarketSource item. Additional charges may apply
Lieferant:
Sampling Systems
Beschreibung:
Der Liquid Master wurde so konzipiert, dass er zur Reinigung schnell zerlegt werden kann.
Lieferant:
HAMMACHER KARL
Beschreibung:
These scalpels are made from Wironit steel (18/12 stainless steel with 18% chrome and from 10 to 12% nickel).
Artikel-Nr:
(461-0500)
Lieferant:
JULABO GmbH
Hersteller-Artikelnummer::
9352793
Lokale Artikelnummer::
JULA9352793
Beschreibung:
Tiefkälte-Umwälzthermostate zum Heizen und Kühlen. Die Geräte sind für externe Temperieranwendungen bei gleichzeitigem Betrieb im Badgefäß konzipiert. Die Einheiten bieten eine besonders anspruchsvolle Heiz- und Kühlleistung mit sehr kurzen Heiz- und Abkühlzeiten selbst bei großvolumigen externen Verbrauchern. Die Modelle FP sind mit Proportional-Kälteleistungsregelung ausgestattet, dadurch energiesparend und mit geringer Abwärme. Modelle mit der Bezeichnung „W“ sind wassergekühlt. Alle Modelle haben Griffe und Laufrollen für einen bequemen Transport sowie eine Ablauföffnung zum einfachen Ablassen der Badflüssigkeit. Die verbesserte Isolierung der mit einer Füllstandsanzeige versehenen Thermostaten verhindert die Bildung von Eis. Typische Anwendungen: Temperieren von doppelwandigen Reaktionsgefäßen, Autoklaven, Miniplant-Installationen, Kilolabors; Gefrierpunktbestimmung; Kalibrierung bei niedrigen Temperaturen und Testen von Petroleum.
VE:
1 * 1 ST
Artikel-Nr:
(214-0342)
Lieferant:
SciLabware
Hersteller-Artikelnummer::
FDE444
Lokale Artikelnummer::
AZLOFDE444
Beschreibung:
PMP, transparent.
VE:
1 * 1 ST
Lieferant:
DWK Life Sciences
Beschreibung:
NS joints with threaded socket, solid.
Artikel-Nr:
(BOSSBS-9047R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A555
Lokale Artikelnummer::
BOSSBS-9047R-A555
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9047R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A647
Lokale Artikelnummer::
BOSSBS-9047R-A647
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY3
Lokale Artikelnummer::
BOSSBS-9067R-CY3
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A555
Lokale Artikelnummer::
BOSSBS-9067R-A555
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A750
Lokale Artikelnummer::
BOSSBS-9067R-A750
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle sise <i>in vivo</i>. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(WITG8.651.004)
Lieferant:
WITEG LABORTECHNIK
Hersteller-Artikelnummer::
8.651.004
Lokale Artikelnummer::
WITG8.651.004
Beschreibung:
Evaporating dishes, made of quartz glass, with spout.
VE:
1 * 1 ST
Artikel-Nr:
(215-1355)
Lieferant:
KARTELL
Hersteller-Artikelnummer::
179
Lokale Artikelnummer::
KART179
Beschreibung:
PE, translucent.
VE:
1 * 1 ST
Artikel-Nr:
(JUCHVL01993/ES)
Lieferant:
JUCHHEIM Laborgeräte GmbH
Hersteller-Artikelnummer::
VL01993/ES
Lokale Artikelnummer::
JUCHVL01993/ES
Beschreibung:
Very strong clips for spherical ground glass joints, made of stainless steel. With screws.
VE:
1 * 1 ST
Artikel-Nr:
(EHERC10490000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C10490000
Lokale Artikelnummer::
EHERC10490000
Beschreibung:
Organic Standard, Benomyl
VE:
1 * 0,25 g
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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