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4-Iodo-3-hydroxypyridine
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4-Iodo-3-hydroxypyridine
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Artikel-Nr:
(BOSSBS-1264R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1264R-CY5.5
Lokale Artikelnummer::
BOSSBS-1264R-CY5.5
Beschreibung:
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1264R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1264R-CY5
Lokale Artikelnummer::
BOSSBS-1264R-CY5
Beschreibung:
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2429R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2429R-A680
Lokale Artikelnummer::
BOSSBS-2429R-A680
Beschreibung:
The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8309R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8309R-A750
Lokale Artikelnummer::
BOSSBS-8309R-A750
Beschreibung:
ANKRD54 is a 300 amino acid protein that contains four ankyrin repeats and is expressed as two alternatively spliced isoforms. The gene encoding human ANKRD54 maps to chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Ethyl-2-chloro-4,4,4-trifluoroacetoacetate 94%
Lieferant:
Thermo Scientific
Beschreibung:
7-Ethyl-10-hydroxycamptothecin 98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-(3-Ethyl-1,2,4-oxadiazol-5-yl)benzoic acid
Artikel-Nr:
(APOSOR4875-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR4875-1G
Lokale Artikelnummer::
APOSOR4875-1G
Beschreibung:
Ethyl-6-chlor-2-methylimidazo[1,2-a]pyridin-3-carboxylat
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-6-bromo-8-fluoroimidazo[1,2-a]pyridine-2-carboxylate
Artikel-Nr:
(H32065.03)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
H32065.03
Lokale Artikelnummer::
ALFAH32065.03
Beschreibung:
Ethyl-2-(trifluoromethyl)-4-methyl-5-pyrimidine carboxylate 97%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-3848R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3848R-FITC
Lokale Artikelnummer::
BOSSBS-3848R-FITC
Beschreibung:
Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context. Displays barbed-end actin capping activity when associated with ABI1, thereby regulating actin-based motility process: capping activity is auto-inhibited and inhibition is relieved upon ABI1 interaction. Also shows actin bundling activity when associated with BAIAP2, enhancing BAIAP2-dependent membrane extensions and promoting filopodial protrusions. Involved in the regulation of processes such as axonal filopodia growth, stereocilia length, dendritic cell migration and cancer cell migration and invasion. Acts as a regulator of axonal filopodia formation in neurons: in the absence of neurotrophic factors, negatively regulates axonal filopodia formation via actin-capping activity. In contrast, it is phosphorylated in the presence of BDNF leading to inhibition of its actin-capping activity and stimulation of filopodia formation. Component of a complex with DFNB31 and MYO15A that localizes at stereocilia tips and is required for elongation of the stereocilia actin core. Indirectly involved in cell cycle progression; its degradation following ubiquitination being required during G2 phase to promote cell shape changes.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR15084-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR15084-25G
Lokale Artikelnummer::
APOSOR15084-25G
Beschreibung:
Ethyl-6-brom-4-hydroxychinolin-3-carboxylat 95%
VE:
1 * 25 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl 5-(Thiophen-2-yl)isoxazole-3-carboxylate 97%
Artikel-Nr:
(APOSOR963490-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR963490-1G
Lokale Artikelnummer::
APOSOR963490-1G
Beschreibung:
Ethyl-2,2-dimethyl-3-oxopyrrolidine-1-carboxylate 95%
VE:
1 * 1 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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