3,5-Dimethoxybenzamidin+Hydrochlorid
Artikel-Nr:
(BOSSBS-6514R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6514R-CY5
Lokale Artikelnummer::
BOSSBS-6514R-CY5
Beschreibung:
CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13472R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13472R-FITC
Lokale Artikelnummer::
BOSSBS-13472R-FITC
Beschreibung:
GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6514R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6514R-CY3
Lokale Artikelnummer::
BOSSBS-6514R-CY3
Beschreibung:
CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8262R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8262R-A680
Lokale Artikelnummer::
BOSSBS-8262R-A680
Beschreibung:
DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterised by severe lung complications and liver dysfunction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9615R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R-A680
Lokale Artikelnummer::
BOSSBS-9615R-A680
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder antitrypsin deficiency. This disorder is characterised by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9617R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9617R-CY7
Lokale Artikelnummer::
BOSSBS-9617R-CY7
Beschreibung:
C14orf174, is a 674 amino acid protein that contains one SAM (sterile alpha motif) domain. Existing as two alternatively spliced isoforms,C14orf174 is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the (14;19) translocations found in a variety of B cell malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(FLUO038691-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
038691-5G
Lokale Artikelnummer::
FLUO038691-5G
Beschreibung:
3',5'-Difluoracetophenon
VE:
1 * 5 g
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Lieferant:
FLUOROCHEM
Beschreibung:
1,3-Dichlor-5-iodbenzol
Artikel-Nr:
(523310-10)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
523310-10
Lokale Artikelnummer::
CALB523310-10
Beschreibung:
Pterostilben, Millipore®
VE:
1 * 10 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
(2-Chlorethyl)dimethylammoniumchlorid, Sigma-Aldrich®
Artikel-Nr:
(SIMECX2082)
Lieferant:
TQC
Hersteller-Artikelnummer::
CX2082
Lokale Artikelnummer::
SIMECX2082
Beschreibung:
Datacable 1500 mm, DB9 female to 3,5 mm stereo jack
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-9741R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9741R-HRP
Lokale Artikelnummer::
BOSSBS-9741R-HRP
Beschreibung:
ANGEL1 , also known as KIAA0759, is a 670 amino acid protein belonging to the CKR-4 protein family. ANGEL1 is encoded by a gene located on human chromosome 14, which contains about 700 genes and 106 million base pairs, making up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus on chromosome 14 and its fusion via translocation with the chromosome 19 encoded protein BCL3 may be related to B-cell malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11733R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-A488
Lokale Artikelnummer::
BOSSBS-11733R-A488
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11861R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11861R-FITC
Lokale Artikelnummer::
BOSSBS-11861R-FITC
Beschreibung:
HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
VE:
1 * 100 µl
Artikel-Nr:
(DENE1010403)
Lieferant:
DEUTSCH NEUMANN
Hersteller-Artikelnummer::
1010403
Lokale Artikelnummer::
DENE1010403
Beschreibung:
Stopper, chloroprene rubber, Rotbraun, Ø unten: 3,5 mm, Ø oben: 6,5 mm, Höhe: 15,0 mm
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-9617R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9617R-A555
Lokale Artikelnummer::
BOSSBS-9617R-A555
Beschreibung:
C14orf174, is a 674 amino acid protein that contains one SAM (sterile alpha motif) domain. Existing as two alternatively spliced isoforms,C14orf174 is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the (14;19) translocations found in a variety of B cell malignancies.
VE:
1 * 100 µl
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