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3,5-Dioxocyclohexanecarboxylic+acid
Artikel-Nr:
(BOSSBS-11861R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11861R-A750
Lokale Artikelnummer::
BOSSBS-11861R-A750
Beschreibung:
HAP1 (huntingtin-associated protein 1) binds to huntingtin. Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region. HAP1 shows neuronal localisation and moves with huntingtin in nerve fibers. HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem. Mouse HAP1 is localised to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons. Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9615R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R-CY5
Lokale Artikelnummer::
BOSSBS-9615R-CY5
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9615R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R-A750
Lokale Artikelnummer::
BOSSBS-9615R-A750
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder antitrypsin deficiency. This disorder is characterised by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterisation.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.This MAb strongly blocks cytotoxicity activity of T4-positive cytotoxic T cell clones.
Lieferant:
Cayman Chemical
Beschreibung:
Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 µM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 µg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss.
Artikel-Nr:
(BOSSBS-11733R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-A488
Lokale Artikelnummer::
BOSSBS-11733R-A488
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11861R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11861R-FITC
Lokale Artikelnummer::
BOSSBS-11861R-FITC
Beschreibung:
HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
VE:
1 * 100 µl
Artikel-Nr:
(WAKO634-03365)
Lieferant:
Wako
Hersteller-Artikelnummer::
634-03365
Lokale Artikelnummer::
WAKO634-03365
Beschreibung:
Wasserstoffperoxid 35%
VE:
1 * 500 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-9615R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R
Lokale Artikelnummer::
BOSSBS-9615R
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9615R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R-CY7
Lokale Artikelnummer::
BOSSBS-9615R-CY7
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(PROOCIL-PCB-95)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-95
Lokale Artikelnummer::
PROOCIL-PCB-95
Beschreibung:
Organic Standard, 2,2',3,5',6-Pentachlorbiphenyl (PCB Nr. 95) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-44)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-44
Lokale Artikelnummer::
PROOCIL-PCB-44
Beschreibung:
Organic Standard, 2,2',3,5'-Tetrachlorbiphenyl (PCB Nr. 44) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-43)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-43
Lokale Artikelnummer::
PROOCIL-PCB-43
Beschreibung:
Organic Standard, 2,2',3,5-Tetrachlorbiphenyl (PCB Nr. 43) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(MAYBRJC02803-1)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
RJC02803-1
Lokale Artikelnummer::
MAYBRJC02803-1
Beschreibung:
2-Methyl-3,5-bis(trifluormethyl)anilin
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-9615R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R-FITC
Lokale Artikelnummer::
BOSSBS-9615R-FITC
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9615R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R-A680
Lokale Artikelnummer::
BOSSBS-9615R-A680
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder antitrypsin deficiency. This disorder is characterised by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterisation.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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