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3,4-(Ethylendioxy)benzylamin
Artikel-Nr:
(HONCR1833-100MG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1833-100MG
Lokale Artikelnummer::
HONCR1833-100MG
Beschreibung:
Honeywell Fluka™ offers an expanding range of high quality inorganic certified reference materials and organic reference materials.
VE:
1 * 100 mg
Artikel-Nr:
(HYPETS-18803)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
TS-18803
Lokale Artikelnummer::
HYPETS-18803
Beschreibung:
Reacti-Block™ aluminium blocks are available with many hole configurations, machine-drilled to accommodate almost any size Reacti-Vial™ small reaction vial, test tube or microcentrifuge tube.
VE:
1 * 1 ST
Lieferant:
Thermo Scientific
Beschreibung:
(±)-3-Chinuclidinol
Lieferant:
Cytiva
Beschreibung:
Superdex prep grade (pg) is produced by covalent bonding of dextran to highly cross-linked agarose.The separation properties of these media are determined by the dextran component
Lieferant:
UPCHURCH SCIENTIFIC
Beschreibung:
These filters are designed to seal and filter simultaneously by incorporating a frit into the body of a flat-bottom ferrule.
Artikel-Nr:
(HONCR1644-100MG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1644-100MG
Lokale Artikelnummer::
HONCR1644-100MG
Beschreibung:
High quality organic reference materials produced according to ISO 9001.
VE:
1 * 100 mg
Artikel-Nr:
(BOSSBS-1135R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1135R-A488
Lokale Artikelnummer::
BOSSBS-1135R-A488
Beschreibung:
c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1135R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1135R-A750
Lokale Artikelnummer::
BOSSBS-1135R-A750
Beschreibung:
c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labelling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr --> Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1135R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1135R-A647
Lokale Artikelnummer::
BOSSBS-1135R-A647
Beschreibung:
c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1135R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1135R-CY5.5
Lokale Artikelnummer::
BOSSBS-1135R-CY5.5
Beschreibung:
c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:
1 * 100 µl
Lieferant:
Agilent
Beschreibung:
These inlet liners prevent adsorption and ensure accurate sample transfer onto the GC column through a robust deactivated surface. These liners are recommended for trace level analysis of active analytes. Liners with inert wool retain non-volatiles, prolonging column life and lowering frequency of MS source maintenance.
Artikel-Nr:
(EHERC11395300)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C11395300
Lokale Artikelnummer::
EHERC11395300
Beschreibung:
4-Chlorbrenzcatechin
VE:
1 * 0,1 g
Artikel-Nr:
(PROOMM0825.02)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0825.02
Lokale Artikelnummer::
PROOMM0825.02
Beschreibung:
(±)-3-Chinuclidinol
VE:
1 * 100 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
(S)-(-)-2-Methyl-CBS-oxazaborolidin 1 mol/l in Toluol, Sigma-Aldrich®
Lieferant:
FLUOROCHEM
Beschreibung:
1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluor-8-iodnonan
Artikel-Nr:
(PRSI91-443)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-443
Lokale Artikelnummer::
PRSI91-443
Beschreibung:
Chymotrypsinogen B (CTRB1) is a 263 amino acid protein with signal peptide (1-18) and Chymotrypsinogen B (19-263). Chymotrypsinogen B have three chains:Chymotrypsin B chain A(19-31), Chymotrypsin B chain B(34-164), Chymotrypsin B chain C (167-263). Chymotrypsinogen B is a Serine Protease Hydrolase secrets into gastrointestinal tract as the inactive precursor Chymotrypsinogen.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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