2-Chloro-N-[4-(trifluoromethyl)phenyl]acetamide
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(1S,2S,3R,5S)-(2,6,6-Trimethyl-3-methylcarbamoyl-bicyclo[3.1.1]hept-2-yl)-carbamic acid tert-butyl ester
Lieferant:
Sigma-Aldrich
Beschreibung:
1,2-Bis(dimethylphosphino)ethan, Sigma-Aldrich®
Lieferant:
Alfa Aesar
Beschreibung:
N-(1-Naphthyl)ethylenediamine Dihydrochlorid 96%
Artikel-Nr:
(BOSSBS-9503R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9503R-A680
Lokale Artikelnummer::
BOSSBS-9503R-A680
Beschreibung:
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
Imidazo[1,2-a]pyridin-6-carbonsäure
Artikel-Nr:
(ENAMEN30003957.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN30003957.1G
Lokale Artikelnummer::
ENAMEN30003957.1G
Beschreibung:
Ethylimidazo[1,2-a]pyridin-2-carboxylat
VE:
1 * 1 g
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Artikel-Nr:
(307432-1L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
307432-1L
Lokale Artikelnummer::
HONC307432-1L
Beschreibung:
1,2-Dimethoxyethan ≥99,9% inhibitorfrei, CHROMASOLV™ für die HPLC, Riedel-de Haën™
VE:
1 * 1 L
Lieferant:
Biotium
Beschreibung:
This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
Lieferant:
Biotium
Beschreibung:
This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
Lieferant:
Biotium
Beschreibung:
This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
Lieferant:
Biotium
Beschreibung:
This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
Lieferant:
COMBI-BLOCKS
Beschreibung:
6-Methylimidazo[1,2-a]pyridin Hydrochlorid
Artikel-Nr:
(APOSOR964961-1KG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR964961-1KG
Lokale Artikelnummer::
APOSOR964961-1KG
Beschreibung:
EDTA Dinatriumsalz 98%
VE:
1 * 1 kg
Lieferant:
COMBI-BLOCKS
Beschreibung:
Ethylimidazo[1,2-a]pyridin-7-carboxylat Hydrochlorid
Artikel-Nr:
(SIALE103-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
E103-1G
Lokale Artikelnummer::
SIALE103-1G
Beschreibung:
EEDQ (Ethyl-N-(2-ethoxy-1,2-dihydrochinolin)carboxylat), Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(24901-25MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
24901-25MG
Lokale Artikelnummer::
SUPL24901-25MG
Beschreibung:
Ionophore employed in solvent polymeric membrane electrodes for the assay of Cl- activity.
VE:
1 * 25 mg
Preis auf Anfrage
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