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Methyl-4-brom-1-naphthoat
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Methyl-4-brom-1-naphthoat
Lieferant:
Alfa Aesar
Beschreibung:
Magnesiumchlorid, ultra trocken ≥99,99% (Metall-Basis)
Lieferant:
Alfa Aesar
Beschreibung:
Bariumchlorid, wasserfrei ≥99,998% (Metall-Basis)
Artikel-Nr:
(SIAL320102-1L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
320102-1L
Lokale Artikelnummer::
SIAL320102-1L
Beschreibung:
Essigsäureanhydrid, Sigma-Aldrich®
VE:
1 * 1 L
Artikel-Nr:
(R004)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
R004
Lokale Artikelnummer::
GENOR004
Beschreibung:
Magnesiumchlorid-Lösung 1 M
VE:
1 * 100 mL
Lieferant:
Alfa Aesar
Beschreibung:
Kaliumchlorid, Optische Qualität
Lieferant:
Sigma-Aldrich
Beschreibung:
Essigsäureanhydrid, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-8687R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8687R-A680
Lokale Artikelnummer::
BOSSBS-8687R-A680
Beschreibung:
p53, a DNA-binding, oligomerisation domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localises to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Magnesiumchlorid, ultra trocken ≥99,9% (Metall-Basis)
Lieferant:
Merck
Beschreibung:
Sebacoyldichlorid zur Synthese, Sigma-Aldrich®
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Methyl Green is a triphenylmethane dye which is mainly used in combination with pyronin. It is suitable for the detection of DNA and RNA. Used in the Methyl Green-Pyronin methods to demonstrate DNA and RNA in tissue sections.
Lieferant:
Merck
Beschreibung:
Hydroxylammoniumchlorid ACS, ISO, Reag. Ph. Eur., GR zur Analyse, Supelco®
Lieferant:
Biotium
Beschreibung:
Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Artikel-Nr:
(BOSSBS-6428R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6428R-CY3
Lokale Artikelnummer::
BOSSBS-6428R-CY3
Beschreibung:
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Lieferant:
Biotium
Beschreibung:
Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Artikel-Nr:
(BOSSBS-12346R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12346R-CY3
Lokale Artikelnummer::
BOSSBS-12346R-CY3
Beschreibung:
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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