Ethyl-2-naphthoyl+formate
Artikel-Nr:
(BOSSBS-1350R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-HRP
Lokale Artikelnummer::
BOSSBS-1350R-HRP
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12402R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12402R-A555
Lokale Artikelnummer::
BOSSBS-12402R-A555
Beschreibung:
RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9425R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9425R-CY7
Lokale Artikelnummer::
BOSSBS-9425R-CY7
Beschreibung:
NET-7, also known as TSPAN15 (tetraspanin 15) or TM4SF15 (transmembrane 4 superfamily member 15), is a 294 amino acid multi-pass membrane protein that belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9425R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9425R-CY5.5
Lokale Artikelnummer::
BOSSBS-9425R-CY5.5
Beschreibung:
NET-7, also known as TSPAN15 (tetraspanin 15) or TM4SF15 (transmembrane 4 superfamily member 15), is a 294 amino acid multi-pass membrane protein that belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9425R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9425R-CY3
Lokale Artikelnummer::
BOSSBS-9425R-CY3
Beschreibung:
NET-7, also known as TSPAN15 (tetraspanin 15) or TM4SF15 (transmembrane 4 superfamily member 15), is a 294 amino acid multi-pass membrane protein that belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13265R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13265R-A555
Lokale Artikelnummer::
BOSSBS-13265R-A555
Beschreibung:
GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9425R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9425R
Lokale Artikelnummer::
BOSSBS-9425R
Beschreibung:
NET-7, also known as TSPAN15 (tetraspanin 15) or TM4SF15 (transmembrane 4 superfamily member 15), is a 294 amino acid multi-pass membrane protein that belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13265R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13265R-A350
Lokale Artikelnummer::
BOSSBS-13265R-A350
Beschreibung:
GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13265R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13265R-A680
Lokale Artikelnummer::
BOSSBS-13265R-A680
Beschreibung:
GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Artikel-Nr:
(BOSSBS-11043R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11043R-HRP
Lokale Artikelnummer::
BOSSBS-11043R-HRP
Beschreibung:
Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11716R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11716R-CY7
Lokale Artikelnummer::
BOSSBS-11716R-CY7
Beschreibung:
CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11272R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11272R-A350
Lokale Artikelnummer::
BOSSBS-11272R-A350
Beschreibung:
Wolfram syndrome protein (WFS1) is an 890 amino acid protein that contains a cytoplasmic N-terminal domain, followed by nine-transmembrane domains and a luminal C-terminal domain. WFS1 is predominantly localized to the endoplasmic reticulum (ER) (1) and its expression is induced in response to ER stress, partially through transcriptional activation (2,3). Research studies have shown that mutations in the WFS1 gene lead to Wolfram syndrome, an autosomal recessive neurodegenerative disorder defined by young-onset, non-immune, insulin-dependent diabetes mellitus and progressive optic atrophy (4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8211R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8211R-A750
Lokale Artikelnummer::
BOSSBS-8211R-A750
Beschreibung:
FAM84B, also known as NSE2 or BCMP101, is a 310 amino acid protein that is expressed in esophageal squamous cell carcinomas, suggesting a role in tumor development and metastasis. The gene encoding FAM84B maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9368R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9368R-A555
Lokale Artikelnummer::
BOSSBS-9368R-A555
Beschreibung:
OCEL1, is a 264 amino acid protein that is encoded by a gene which maps to human chromosome 19. Chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-A488
Lokale Artikelnummer::
BOSSBS-8345R-A488
Beschreibung:
FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
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