3-Amino-5-chloro-4-hydroxybenzotrifluoride
Artikel-Nr:
(BOSSBS-12992R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12992R-A647
Lokale Artikelnummer::
BOSSBS-12992R-A647
Beschreibung:
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6728R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6728R-A488
Lokale Artikelnummer::
BOSSBS-6728R-A488
Beschreibung:
Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1595R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1595R-A488
Lokale Artikelnummer::
BOSSBS-1595R-A488
Beschreibung:
spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6480R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6480R-A555
Lokale Artikelnummer::
BOSSBS-6480R-A555
Beschreibung:
Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5154R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5154R-A680
Lokale Artikelnummer::
BOSSBS-5154R-A680
Beschreibung:
May play a role in mediating neutrophil activation and chemotaxis. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2075R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2075R-A647
Lokale Artikelnummer::
BOSSBS-2075R-A647
Beschreibung:
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6536R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6536R-A555
Lokale Artikelnummer::
BOSSBS-6536R-A555
Beschreibung:
Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8190R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8190R-A647
Lokale Artikelnummer::
BOSSBS-8190R-A647
Beschreibung:
CSMD3 belongs to the CSMD family and contains fourteen CUB domains and twenty eight Sushi (CCP/SCR) domains. It is weakly expressed in most tissues, except in brain; expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis. There are five named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7102R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7102R-A647
Lokale Artikelnummer::
BOSSBS-7102R-A647
Beschreibung:
Pseudouridination is the isomerization of uridine to pseudouridine. It is the most common posttranscriptional nucleotide modification found in RNA. It is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones which facilitate the correct folding and assembly of tRNAs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5733R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5733R-A750
Lokale Artikelnummer::
BOSSBS-5733R-A750
Beschreibung:
Adapter protein involved in asymmetrical cell division and cell polarisation processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5811R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5811R-A750
Lokale Artikelnummer::
BOSSBS-5811R-A750
Beschreibung:
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8190R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8190R-A350
Lokale Artikelnummer::
BOSSBS-8190R-A350
Beschreibung:
CSMD3 belongs to the CSMD family and contains fourteen CUB domains and twenty eight Sushi (CCP/SCR) domains. It is weakly expressed in most tissues, except in brain; expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis. There are five named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1992R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1992R-A488
Lokale Artikelnummer::
BOSSBS-1992R-A488
Beschreibung:
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2032R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2032R-A350
Lokale Artikelnummer::
BOSSBS-2032R-A350
Beschreibung:
PMP2 is a small basic protein, belonging to the fatty-acid binding protein (FABP) family and is one of the major proteins of peripheral myelin. It appears to be involved in the transport of fatty acids or the metabolism of myelin lipids, and has been shown to have lipid-binding activity. PMP2 protein may have an important role in the organization of compact myelin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8615R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8615R-A488
Lokale Artikelnummer::
BOSSBS-8615R-A488
Beschreibung:
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6294R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6294R-A555
Lokale Artikelnummer::
BOSSBS-6294R-A555
Beschreibung:
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
VE:
1 * 100 µl
Preis auf Anfrage
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