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3-Aminopiperidine+hydrochloride,+N1-CBZ+protected
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3-Aminopiperidine+hydrochloride,+N1-CBZ+protected
Artikel-Nr:
(139-0223)
Lieferant:
HONEYWELL SAFETY
Hersteller-Artikelnummer::
1008360
Lokale Artikelnummer::
DALL1008360
Beschreibung:
Anschlagschlinge aus Gurtband zur Verwendung mit einem persönlichen Fallbegrenzer bei Arbeiten mit wenig Sturzraum. Zur Befestigung von Höhensicherungsgeräten, Sicherheitsseilen oder Fallbegrenzern.
VE:
1 * 1 ST
Lieferant:
LACONT UMWELTTECHNIK
Beschreibung:
Fire protection container is suitable for indoor and outdoor use. Fire resistant: 90 m.
Lieferant:
Showa
Beschreibung:
These powder-free disposable gloves are made from 100% nitrile. They provide protection against the penetration and projection of chemicals.
Lieferant:
Biotium
Beschreibung:
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Deoxyribonucleic acid (DNA) is a long polymer of nucleotides that is held together by a backbone made of sugars and phosphate groups. It holds the genetic instructions for the development and function of living things. DNA is crucial for living organisms, and all known cellular life and some viruses contain DNA. In eukaryotes, DNA exists in the cell nucleus, while in prokaryotes; DNA is located in the cytoplasm. In living organisms, DNA does not usually exist as a single molecule, but instead as a tightly associated pair of molecules in the shape of a right-handed double helix. Hydrogen bonds as well as forces generated by the hydrophobic effect and pi stacking hold the two DNA strands together. During replication and transcription, portions of the helix unwind and become single stranded. Protective proteins surround these single-stranded DNA. Double stranded (ds) DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.
Lieferant:
Biotium
Beschreibung:
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Deoxyribonucleic acid (DNA) is a long polymer of nucleotides that is held together by a backbone made of sugars and phosphate groups. It holds the genetic instructions for the development and function of living things. DNA is crucial for living organisms, and all known cellular life and some viruses contain DNA. In eukaryotes, DNA exists in the cell nucleus, while in prokaryotes; DNA is located in the cytoplasm. In living organisms, DNA does not usually exist as a single molecule, but instead as a tightly associated pair of molecules in the shape of a right-handed double helix. Hydrogen bonds as well as forces generated by the hydrophobic effect and pi stacking hold the two DNA strands together. During replication and transcription, portions of the helix unwind and become single stranded. Protective proteins surround these single-stranded DNA. Double stranded (ds) DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.
Artikel-Nr:
(BOSSBS-11670R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11670R-A680
Lokale Artikelnummer::
BOSSBS-11670R-A680
Beschreibung:
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. Probably forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Its activity is dependent on MBD1 and is heritably maintained through DNA replication by being recruited by CAF-1. SETDB1 is targeted to histone H3 by TRIM28/TIF1B, a factor recruited by KRAB zinc-finger proteins. Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumour suppressor genes (TSGs) or other tumour-related genes in colorectal cancer (CRC) cells (PubMed:24623306). Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs) (PubMed:24623306). Associates at promoter regions of tumour suppressor genes (TSGs) leading to their gene silencing (PubMed:24623306). The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI27-304)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-304
Lokale Artikelnummer::
PRSI27-304
Beschreibung:
TERF2 is a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 100 µG
Lieferant:
LABCON
Beschreibung:
ProtectR® tube is the only container closure system engineered to be CO₂ resistant and stop costly damage to molecular and cellular solutions when using dry ice. Made of durable, high-quality materials and fitted with an air-tight cap, ProtectR® Tubes form a protective barrier impermeable to CO₂, keeping the sample pH stable and preventing acidification.
Lieferant:
UVEX
Beschreibung:
Die ultraleichte Bügelbrille aus Hightech-Polymer verfügt über eine robuste Fassung und ein neuentwickeltes Bügelkonzept mit angenehm weichen, flexiblen Bügeln. Die Super G gewährleistet einen komfortablen, druckfreien Sitz für ermüdungsfreies Arbeiten.
Lieferant:
UVEX
Beschreibung:
Die Super OTG verfügt über scharnierlose Bügel aus Grilamid. Sie vereint die Vorteile der Bügelbrille mit den Trageeigenschaften von Kopfbändern.
Artikel-Nr:
(CORN6078)
Lieferant:
Corning
Hersteller-Artikelnummer::
6078
Lokale Artikelnummer::
CORN6078
Beschreibung:
Enrty module power on/off switch with overload protection
VE:
1 * 1 Pack.
Lieferant:
MENSCH FRANZ
Beschreibung:
Diese HACCP-konforme Einweg-Kittel aus PP-Vlies schützt hygiene-sensible Bereiche vor Verunreinigungen und ist besonders leicht und atmungsaktiv.
Lieferant:
3M
Beschreibung:
3M™ Allzweckklebebänder aus Vinyl und mit einem Gummikleber beschichtet. Man verwendet sie für unkritische Anwendungen wie Farbkodierungen, Bündel- und Sicherheitsmarkierung, temporäre Markierung von Teilen und Maschinen, zum Schutz von Teilen und Ausrüstung oder zum Schutz vor Abnutzung.
Lieferant:
SIOEN PERSONAL PROTECTIVE CLOT
Beschreibung:
Schützende, zweifarbige Jacke aus 100 % weichem, doppelseitigem Polyester-Fleece für einen guten Schutz vor Kälte. Mit Antipilling-Behandlung und Saumnähten. Kann mit einem Reißverschluss in die Regenjacke 608Z eingesetzt werden.
Artikel-Nr:
(BOSSBS-5130R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5130R-A750
Lokale Artikelnummer::
BOSSBS-5130R-A750
Beschreibung:
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate p53/TP53 in the presence of supercoiled DNA is dependent on C1D. Contributes to the determination of the circadian period length by antagonizing phosphorylation of CRY1 'Ser-588' and increasing CRY1 protein stability, most likely through an indirect machanism. Interacts with CRY1 and CRY2; negatively regulates CRY1 phosphorylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1359R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1359R-HRP
Lokale Artikelnummer::
BOSSBS-1359R-HRP
Beschreibung:
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate p53/TP53 in the presence of supercoiled DNA is dependent on C1D. Contributes to the determination of the circadian period length by antagonizing phosphorylation of CRY1 'Ser-588' and increasing CRY1 protein stability, most likely through an indirect machanism. Interacts with CRY1 and CRY2; negatively regulates CRY1 phosphorylation.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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