3-Amino-4-fluorobenzo[b]thiophene-2-carboxylic+acid
Artikel-Nr:
(BOSSBS-9095R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9095R-A750
Lokale Artikelnummer::
BOSSBS-9095R-A750
Beschreibung:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localises to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
VE:
1 * 100 µl
Lieferant:
Cayman Chemical
Beschreibung:
Rivastigmine is an irreversible inhibitor of acetylcholinesterase (IC<sub>50</sub>=4,15 µm) and butyrylcholinesterase (IC<sub>50</sub>=37 nM).
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
C.I. 42655
Artikel-Nr:
(BOSSBS-11670R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11670R-A647
Lokale Artikelnummer::
BOSSBS-11670R-A647
Beschreibung:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
VE:
1 * 100 µl
Artikel-Nr:
(A3480.0025)
Lieferant:
PanReac AppliChem
Hersteller-Artikelnummer::
A3480.0025
Lokale Artikelnummer::
APLIA3480.0025
Beschreibung:
Coomassie Brillantblau G 250
VE:
1 * 25 g
Artikel-Nr:
(40013.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
40013
Lokale Artikelnummer::
BTIU40013
Beschreibung:
PMA (propidium monoazide) is a high-affinity photoreactive DNA binding dye invented by scientists at Biotium for viability PCR of bacteria and other organisms. The dye is weakly fluorescent by itself but becomes more fluorescent after binding to nucleic acids.
VE:
1 * 1 mg
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Brilliant Blue R has been used in staining of gels after electrophoresis. It has also been used to determine protein in the protein bodies. For detection of protein bands following electrophoresis.
Artikel-Nr:
(BOSSBS-11670R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11670R-A488
Lokale Artikelnummer::
BOSSBS-11670R-A488
Beschreibung:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13026R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13026R-A750
Lokale Artikelnummer::
BOSSBS-13026R-A750
Beschreibung:
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0473R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0473R-CY3
Lokale Artikelnummer::
BOSSBS-0473R-CY3
Beschreibung:
Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0473R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0473R-CY5.5
Lokale Artikelnummer::
BOSSBS-0473R-CY5.5
Beschreibung:
Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2379R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2379R-CY3
Lokale Artikelnummer::
BOSSBS-2379R-CY3
Beschreibung:
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Appearance: White to light green to light brown Crystalline powder
Artikel-Nr:
(BOSSBS-2379R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2379R-A750
Lokale Artikelnummer::
BOSSBS-2379R-A750
Beschreibung:
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0473R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0473R-A555
Lokale Artikelnummer::
BOSSBS-0473R-A555
Beschreibung:
Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0473R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0473R-A750
Lokale Artikelnummer::
BOSSBS-0473R-A750
Beschreibung:
Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialisation, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
VE:
1 * 100 µl
Preis auf Anfrage
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