3-Amino-5-chloro-4-hydroxybenzotrifluoride
Artikel-Nr:
(BOSSBS-6217R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6217R-A647
Lokale Artikelnummer::
BOSSBS-6217R-A647
Beschreibung:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts. Regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, CRY1 and NR1D1 itself, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, leading to the circadian pattern of clock genes expression. Therefore influences the period length and stability of the clock. Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, including PLIN2 and AVPR1A. Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, such as MMP3. Controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity. In liver, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, steroids and xenobiotics, such as SULT1E1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6217R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6217R-A680
Lokale Artikelnummer::
BOSSBS-6217R-A680
Beschreibung:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts. Regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, CRY1 and NR1D1 itself, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, leading to the circadian pattern of clock genes expression. Therefore influences the period length and stability of the clock. Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, including PLIN2 and AVPR1A. Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, such as MMP3. Controls adipogenesis as well as adipocyte sise and modulates insulin sensitivity in obesity. In liver, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, steroids and xenobiotics, such as SULT1E1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6217R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6217R-A750
Lokale Artikelnummer::
BOSSBS-6217R-A750
Beschreibung:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts. Regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, CRY1 and NR1D1 itself, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, leading to the circadian pattern of clock genes expression. Therefore influences the period length and stability of the clock. Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, including PLIN2 and AVPR1A. Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, such as MMP3. Controls adipogenesis as well as adipocyte sise and modulates insulin sensitivity in obesity. In liver, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, steroids and xenobiotics, such as SULT1E1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6217R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6217R-A488
Lokale Artikelnummer::
BOSSBS-6217R-A488
Beschreibung:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts. Regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, CRY1 and NR1D1 itself, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, leading to the circadian pattern of clock genes expression. Therefore influences the period length and stability of the clock. Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, including PLIN2 and AVPR1A. Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, such as MMP3. Controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity. In liver, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, steroids and xenobiotics, such as SULT1E1.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI34-204)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-204
Lokale Artikelnummer::
PRSI34-204
Beschreibung:
It reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to BrdU is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors.
VE:
1 * 100 µG
Artikel-Nr:
(APOSOR81875-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR81875-100MG
Lokale Artikelnummer::
APOSOR81875-100MG
Beschreibung:
6,6',6''-(Benzene-1,3,5-triyl)tris(2-naphthoic acid) 100mg pack 1 * 100 mg
VE:
1 * 100 mg
New Product
Artikel-Nr:
(APOSOR1009148-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1009148-25G
Lokale Artikelnummer::
APOSOR1009148-25G
Beschreibung:
1,3,5-Tris(1-Phenyl-1H-Benzo[D]Imidazol-2-Yl)Benzene 25g pack 1 * 25 g
VE:
1 * 25 g
New Product
Artikel-Nr:
(APOSIN10626-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
IN10626-250MG
Lokale Artikelnummer::
APOSIN10626-250MG
Beschreibung:
Trans-Dibromo[Bis(Tri-O-Tolylphosphine)]Palladium(II) 250mg pack 1 * 250 mg
VE:
1 * 250 mg
New Product
Artikel-Nr:
(APOSBICL4218-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BICL4218-100MG
Lokale Artikelnummer::
APOSBICL4218-100MG
Beschreibung:
3,4,6-Tri-O-benzyl-1,2-O-(1-methoxyethylidene)-beta-D-mannopyranose 100mg pack 1 * 100 mg
VE:
1 * 100 mg
New Product
Artikel-Nr:
(APOSBICL4374-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BICL4374-250MG
Lokale Artikelnummer::
APOSBICL4374-250MG
Beschreibung:
3,4,6-Tri-O-acetyl-1,2-O-(1-methoxyethylidene)-beta-D-mannopyranose 250mg pack 1 * 250 mg
VE:
1 * 250 mg
New Product
Artikel-Nr:
(APOSIN10626-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
IN10626-100MG
Lokale Artikelnummer::
APOSIN10626-100MG
Beschreibung:
Trans-Dibromo[Bis(Tri-O-Tolylphosphine)]Palladium(II) 100mg pack 1 * 100 mg
VE:
1 * 100 mg
New Product
Artikel-Nr:
(APOSBICL2576-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BICL2576-1G
Lokale Artikelnummer::
APOSBICL2576-1G
Beschreibung:
2,3,4-Tri-O-acetyl-1-(N-phenyl)trifluoroacetimidoyl-D-glucopyranuronic acid methyl ester 1g pack 1 * 1 g
VE:
1 * 1 g
New Product
Artikel-Nr:
(APOSPC105451-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC105451-250MG
Lokale Artikelnummer::
APOSPC105451-250MG
Beschreibung:
Tris(acetonitrile)(pentamethylcyclopentadienyl)rhodium(III) bis(hexafluoroantimonate) 250mg pack 1 * 250 mg
VE:
1 * 250 mg
New Product
Artikel-Nr:
(APOSOR80137-500G)
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,3,5-Tris(3-(trimethoxysilyl)propyl)-1,3,5-triazinane-2,4,6-trione 500g pack 1 * 500 g
VE:
New Product
Artikel-Nr:
(APOSIN10542-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
IN10542-1G
Lokale Artikelnummer::
APOSIN10542-1G
Beschreibung:
Methanesulfonato(Tri-T-Butylphosphino)(2’-Methylamino-1,1’-Biphenyl-2-Yl)Palladium(Ii) 1g pack 1 * 1 g
VE:
1 * 1 g
New Product
Artikel-Nr:
(APOSPC99637-250MG)
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Tris(2,2'-bipyridine)cobalt(II) bis(hexafluorophosphate) 250mg pack 1 * 250 mg
VE:
New Product
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