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3-Fluor-4-methoxybenzylamin
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3-Fluor-4-methoxybenzylamin
Artikel-Nr:
(BOSSBS-6518R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6518R-A488
Lokale Artikelnummer::
BOSSBS-6518R-A488
Beschreibung:
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1893R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1893R-A555
Lokale Artikelnummer::
BOSSBS-1893R-A555
Beschreibung:
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1333R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1333R-A350
Lokale Artikelnummer::
BOSSBS-1333R-A350
Beschreibung:
This gene encodes a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm. Once apoptosis is induced, the level of this protein increases and by relocation from the cytoplasm, it accumulates in the nucleus. Although its exact function is not defined, this protein is thought to play an early and universal role in apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5767R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5767R-A750
Lokale Artikelnummer::
BOSSBS-5767R-A750
Beschreibung:
Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4848R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4848R-A488
Lokale Artikelnummer::
BOSSBS-4848R-A488
Beschreibung:
RUNX3 binds to the core site of murine Leukemia virus, the core sequences in the enhancer of the polyomavirus, and also to the enhancers of the T-cell receptor genes. May be involved in the control of cellular proliferation and/or differentiation (By similarity). Heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer and through the Runt domain.DNA-binding is increased by heterodimerization. Interacts with TLE1 and SUV39H1, Subcellular location in Nucleus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8525R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8525R-A647
Lokale Artikelnummer::
BOSSBS-8525R-A647
Beschreibung:
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6601R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6601R-A488
Lokale Artikelnummer::
BOSSBS-6601R-A488
Beschreibung:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10421R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10421R-A488
Lokale Artikelnummer::
BOSSBS-10421R-A488
Beschreibung:
Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells. It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. It may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. (referenced from swissprot)
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1432R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1432R-A555
Lokale Artikelnummer::
BOSSBS-1432R-A555
Beschreibung:
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2418R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2418R-A750
Lokale Artikelnummer::
BOSSBS-2418R-A750
Beschreibung:
Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3187R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3187R-A647
Lokale Artikelnummer::
BOSSBS-3187R-A647
Beschreibung:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8539R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8539R-A555
Lokale Artikelnummer::
BOSSBS-8539R-A555
Beschreibung:
Luciferase from the firefly has become one of the more widely used reporter proteins for the study of gene expression. Luciferase catalyzes a bioluminescent reaction which requires the substrate luciferin as well as Mg2+ and ATP. Mixing these reagents with the cell extract containing luciferase, results in a flash of light that decays rapidly. This light can be detected by a luminometer. The total light emission is proportional to the luciferase activity of the sample.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4173R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4173R-A647
Lokale Artikelnummer::
BOSSBS-4173R-A647
Beschreibung:
Twist2 (Twist homolog 2) is a basic helix-loop-helix (bHLH) transcription factor which acts as a transcriptional repressor. It binds to the E-box consensus sequence 5'-CANNTG-3' and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Efficient DNA binding requires dimerization with another bHLH protein. Twist2 inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11204R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11204R-A750
Lokale Artikelnummer::
BOSSBS-11204R-A750
Beschreibung:
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2602R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2602R-A555
Lokale Artikelnummer::
BOSSBS-2602R-A555
Beschreibung:
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8719R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8719R-A680
Lokale Artikelnummer::
BOSSBS-8719R-A680
Beschreibung:
Leucine-rich protein (LRP130) is a cytoplasmic mRNA-binding protein likely to be involved in the processing of mitochondrial DNA transcripts. Defects in the LRPPRC gene that encodes LRP130 result in the French-Canadian type of Leigh syndrome, a severe neurological disorder characterised by lesions in the subcortical region of the brain. LRP130 also interacts with the low-affinity receptor for leukemia inhibitory factor to produce an intracelluar signal cascade.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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