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3-Fluor-4-methoxybenzylamin
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3-Fluor-4-methoxybenzylamin
Artikel-Nr:
(BOSSBS-11649R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11649R-A488
Lokale Artikelnummer::
BOSSBS-11649R-A488
Beschreibung:
The NGG1 interacting factor 3-like 1 (NIF3L1) is a 377 amino acid protein expressed mainly in the cytoplasm of cells in several different tissues. It has been highly conserved throughout evolution, from bacteria to mammals. NIF3L participates in retinoic acid-primed neural differentiation of P19 embryonic carcinoma cells by cooperating with Trip15/CSN2, a transcriptional corepressor/component of COP9 signalosome. NIF3L1 interacts with itself and with the NIF3L1 binding protein 1 (NIF3L1 BP1), which is a novel protein presumed to contain a leucine zipper domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5550R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5550R-A647
Lokale Artikelnummer::
BOSSBS-5550R-A647
Beschreibung:
Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4989R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4989R-A647
Lokale Artikelnummer::
BOSSBS-4989R-A647
Beschreibung:
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-A647
Lokale Artikelnummer::
BOSSBS-6947R-A647
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4595R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4595R-A750
Lokale Artikelnummer::
BOSSBS-4595R-A750
Beschreibung:
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3535R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3535R-A647
Lokale Artikelnummer::
BOSSBS-3535R-A647
Beschreibung:
PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6420R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6420R-A647
Lokale Artikelnummer::
BOSSBS-6420R-A647
Beschreibung:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12392R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12392R-A647
Lokale Artikelnummer::
BOSSBS-12392R-A647
Beschreibung:
TLE5 is a 197 amino acid nuclear protein that belongs to the TLE family. Expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle, TLE5 functions as either a homooligomer or a heterooligomer with other TLE family members and, through this association, dominantly represses the expression of TLE genes. In addition, TLE5 can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Two isoforms of TLE5 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4901R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4901R-A488
Lokale Artikelnummer::
BOSSBS-4901R-A488
Beschreibung:
The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7554R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7554R-A350
Lokale Artikelnummer::
BOSSBS-7554R-A350
Beschreibung:
Eph receptor A2 is the receptor for members of the ephrin-A family. It binds to ephrin-A1, -A3, -A4 and -A5. Eph receptor A3 is also a receptor for members of the ephrin-A family. It binds to ephrin-A2, -A3, -A4 and -A5 and is thought to play a role in lymphoid function. Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5. It binds more poorly to ephrin-A2 and -A3. It may play a role in a signal transduction process involved in hindbrain pattern formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3521R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3521R-A488
Lokale Artikelnummer::
BOSSBS-3521R-A488
Beschreibung:
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0953R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0953R-A488
Lokale Artikelnummer::
BOSSBS-0953R-A488
Beschreibung:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5005R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5005R-A647
Lokale Artikelnummer::
BOSSBS-5005R-A647
Beschreibung:
PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. It has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFKFB2 regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2578R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2578R-A555
Lokale Artikelnummer::
BOSSBS-2578R-A555
Beschreibung:
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-A488
Lokale Artikelnummer::
BOSSBS-6947R-A488
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9413R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9413R-A750
Lokale Artikelnummer::
BOSSBS-9413R-A750
Beschreibung:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterised by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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