(S)-3-Amino-5-hexynoic+acid+hydrochloride
Artikel-Nr:
(PRSI7641)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7641
Lokale Artikelnummer::
PRSI7641
Beschreibung:
The G protein–coupled receptor kinases (GRKs) are a versatile family of kinases that play a critical role in cancer metastasis through their regulation of G-protein coupled receptors (GPCRs) involved in growth factor mediated cell migration (1,2). Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state. GRK6 is one of 7 members of the GRK serine/threonine kinase subfamily, which has been shown to modulate the Wnt signaling pathway via phosphorylation of LRP6 (3,4), and the insulin-like growth factor signaling pathway. GRK6 may also play a role in immune system function.
VE:
1 * 100 µG
Lieferant:
BACHEM BIOCHEMICA
Beschreibung:
Dithiothreitol (DTT, Cleland's Reagenz)
Artikel-Nr:
(PRSI5743)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5743
Lokale Artikelnummer::
PRSI5743
Beschreibung:
PIAS2 Antibody: The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS2. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS2 binds specifically to STAT4 following IL-12 stimulation and inhibits STAT4-mediated gene activation in human T cells. PIAS2 is a potent transcriptional activator of Bcl-2, but together with Bcl-6 can suppress the expression of Bcl-2.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-490)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-490
Lokale Artikelnummer::
PRSI91-490
Beschreibung:
CD98 is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2/MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and amino acid transport function of the light chains. It is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. It also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes.
VE:
1 * 50 µG
Lieferant:
Thermo Fisher Scientific
Beschreibung:
Dank dieser Pipetten mit verbesserter Vielseitigkeit können tägliche Pipettieraufgaben mit 96- und 384-Well-Mikroplatten automatisiert werden. Ein elektronischer Spitzenabwurf und die ergonomische Zeigefingerbedienung ermöglichen eine Entspannung des Daumens beim Pipettieren.
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Artikel-Nr:
(662-1581)
Lieferant:
Thermo Orion
Hersteller-Artikelnummer::
8220BNWP
Lokale Artikelnummer::
ORIO8220BNWP
Beschreibung:
This pH electrode is ideal for measuring micro volume samples. A PTFE protective sleeve over the glass stem provides greater durability than conventional micro pH electrodes and allows pH and temperature measurement of samples in 384 well plates or samples.
Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.
VE:
1 * 1 ST
Artikel-Nr:
(REST31620)
Lieferant:
Restek
Hersteller-Artikelnummer::
31620
Lokale Artikelnummer::
REST31620
Beschreibung:
Contains: Aramite (140-57-8); Bis(2-chloroethyl)ether (111-44-4); Bis(2-chloroethoxy)methane (111-91-1); 4-Bromophenyl phenyl ether (101-55-3); Chlorobenzilate (510-15-6); 2-Chloronaphthalene (91-58-7); 4-Chlorophenyl phenyl ether (7005-72-3); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,3-Dinitrobenzene (99-65-0); Hexachlorobenzene (118-74-1); Hexachlorobutadiene (87-68-3); Hexachlorocyclopentadiene (77-47-4); Hexachloroethane (67-72-1); Hexachloropropene (1888-71-7); Isodrin (465-73-6); Kepone (143-50-0); 2,2'-Oxybis(1-chloropropane) (108-60-1); Pentachlorobenzene (608-93-5); Pentachloronitrobenzene (quintozene) (82-68-8); 1,2,4,5-Tetrachlorobenzene (95-94-3); 1,2,4-Trichlorobenzene (120-82-1)
VE:
1 * 1 mL
Artikel-Nr:
(SERA30060.01)
Lieferant:
Serva
Hersteller-Artikelnummer::
30060.01
Lokale Artikelnummer::
SERA30060.01
Beschreibung:
N-(1-Naphthyl)ethylenediamine Dihydrochlorid
VE:
1 * 5 g
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Artikel-Nr:
(PRSI6953)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6953
Lokale Artikelnummer::
PRSI6953
Beschreibung:
TCTEX1D2 Antibody: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D2, also called TCTEX1 domain containing 2, belongs to the dynein light chain TCTEX-type family. Its function is still under investigation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6957)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6957
Lokale Artikelnummer::
PRSI6957
Beschreibung:
TCTEX1D4 Antibody: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D4, also called TCTEX2 beta, interacts with different members of the TGF-beta receptor family, and when overexpressed, inhibits TGF-beta signaling.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5473)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5473
Lokale Artikelnummer::
PRSI5473
Beschreibung:
SRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-343)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-343
Lokale Artikelnummer::
PRSI91-343
Beschreibung:
Lumican is a 40 kD secreted protein which belongs to the small leucine-rich repeat proteoglycans (SLRPs) and the class II subfamily. Human Lumican is synthesized as a 338 amino acid precursor then cut the 18 aa signal sequence. The mature Human Lumican contains 12 leucine-rich repeats (LRRs), 4 potential sites of N-linked glycosylation, and a C- terminal with two conserved cyst-eines. Lumican can be existed in extracellular matrix of human articular cartilage. Lumican participates in the maintenance of tissue homeostasis and regulates cellular functions in vivo, such as cell proliferation, adhesion, migration, and differentiation. The overexpression of lumican has been correlated to colorectal tumor, breast, neuroendocrine, and pancreatic cancers.
VE:
1 * 50 µG
Lieferant:
Portwest Clothing
Beschreibung:
Bleiben Sie sichtbar und fühlen Sie sich wohl in dieser Jacke von hervorragender Qualität. Das einzigartige leichte Material bietet eine unübertroffene Kombination aus Atmungsaktivität sowie Wasser- und Windschutz.
Artikel-Nr:
(PRSI76-074)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-074
Lokale Artikelnummer::
PRSI76-074
Beschreibung:
The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.2, expressed on thymocytes, mature T cells, epithelial cells, neurons, hematopoietic stem cells, and fibroblasts. CD90 is a membrane glycoprotein that regulates the adhesion and signal transduction in T lymphocytes, and the adhesion of thymocytes to thymic stroma. The interaction between 30-H12 and the antibody to the CD3/TCR complex upregulates thymocytes signal transduction and apoptosis and downregulates mature T cell proliferation. The 30-H12 antibody seems to be unable to cross-link with CD90.1.
VE:
1 * 0,1 mg
New Product
Lieferant:
Sigma-Aldrich
Beschreibung:
N-(1-Naphthyl)ethylenediamine Dihydrochlorid, Sigma-Aldrich®
Preis auf Anfrage
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