4,4-Dimethylcyclohexa-1,5-dienylborons\u00E4ure+Mononatriumsalz
Artikel-Nr:
(BOSSBS-1764R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1764R-CY3
Lokale Artikelnummer::
BOSSBS-1764R-CY3
Beschreibung:
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.
VE:
1 * 100 µl
Artikel-Nr:
(PERCN9306510)
Lieferant:
PERKIN ELMER GC INSTRUMENTS
Hersteller-Artikelnummer::
N9306510
Lokale Artikelnummer::
PERCN9306510
Beschreibung:
SPE Supra-Poly® extreme capacity wide pore (XWP) are polymer based columns, polystyrene-divinylbenzene (PSDVB). Ideal for extracting polar and non-polar compounds when analysing drugs and drug metabolites in biological fluids.
VE:
1 * 1 ST
Lieferant:
AESCULAP AG
Beschreibung:
Complete set of uterine dilators.
Artikel-Nr:
(HEWL125-1912)
Lieferant:
Agilent
Hersteller-Artikelnummer::
125-1912
Lokale Artikelnummer::
HEWL125-1912
Beschreibung:
Sie sind mit Lösungsmittel abspülbar sowie geringes Bluten und haben eine Säule mit niedriger oder mittlerer Polarität ideal für GC/ GC. Sie eignen sich für CLP-Pestizide.
VE:
1 * 1 ST
Artikel-Nr:
(HYPE60108-707)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
60108-707
Lokale Artikelnummer::
HYPE60108-707
Beschreibung:
Solid phase extraction cartridges, HyperSep™ phenyl offer alternative selectivity for retention of basic compounds. They are used for extraction of aromatic compounds and extraction of basic analytes.
VE:
1 * 20 ST
Artikel-Nr:
(SIAL250066-100ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
250066-100ML
Lokale Artikelnummer::
SIAL250066-100ML
Beschreibung:
Aluminiumbromid 1 mol/l in Dibrommethan, Sigma-Aldrich®
VE:
1 * 100 mL
Lieferant:
EPPENDORF
Beschreibung:
For any application that requires sample/reaction mixing and heating the Eppendorf® ThermoMixer F family is what you need. Whether you work with 0,5/1,5/2,0 ml tubes or plates (MTP and DWP) the dedicated fixed blocks offer a perfect solution for your special application.
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Lieferant:
NEW PIG
Beschreibung:
Modular deck system ideal to create a customised drum storage area that shares sump capacity. With flow-through sump design liquid passes freely from one sump to another.
Lieferant:
IKA
Beschreibung:
Laborrührwerk für einfache Rühraufgaben bis zu 15 oder 25 L (EUROSTAR 20 digital und EUROSTAR 40 digital), oder für intensive Rühraufgaben bis zu 20 L (EUROSTAR 20 high speed digital). Eine mikroprozessorgesteuerte Regelung hält die zwischen 0/30 – 2.000 min-1 (oder 0/150 – 6000 für das High-Speed-Model) eingestellte Drehzahl konstant. Ein elektronischer Sicherheitskreis garantiert das Abschalten des Gerätes im Fehlerfall oder bei Überlastung. Soll- und Ist-Drehzahl werden kontinuierlich überwacht und automatisch angeglichen. So bleibt die Geschwindigkeit auch dann konstant, wenn sich die Viskosität des Mediums ändert.
Artikel-Nr:
(EUTEECCONWP60043K)
Lieferant:
EUTECH
Hersteller-Artikelnummer::
ECCONWP60043K
Lokale Artikelnummer::
EUTEECCONWP60043K
Beschreibung:
The waterproof, portable conductivity/TDS meter features a broad conductivity range with auto-ranging capabilities for more convenience.
VE:
1 * 1 SET
Artikel-Nr:
(SIAL385514-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
385514-5G
Lokale Artikelnummer::
SIAL385514-5G
Beschreibung:
(S)-(-)-2-Brompropionsäure, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(SIAL278084-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
278084-25G
Lokale Artikelnummer::
SIAL278084-25G
Beschreibung:
3-Nitrophthalhydrazid, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-0573R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0573R-A350
Lokale Artikelnummer::
BOSSBS-0573R-A350
Beschreibung:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. Transcript Variant: This variant (1) contains a different 5' end region, which includes an upstream in-frame translation start codon, when compared to variant 2. The encoded protein has a 15 aa longer N-terminus, as compared to isoform 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1764R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1764R-HRP
Lokale Artikelnummer::
BOSSBS-1764R-HRP
Beschreibung:
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0573R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0573R-A488
Lokale Artikelnummer::
BOSSBS-0573R-A488
Beschreibung:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. Transcript Variant: This variant (1) contains a different 5' end region, which includes an upstream in-frame translation start codon, when compared to variant 2. The encoded protein has a 15 aa longer N-terminus, as compared to isoform 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0573R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0573R-A750
Lokale Artikelnummer::
BOSSBS-0573R-A750
Beschreibung:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterised by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. Transcript Variant: This variant contains a different 5' end region, which includes an upstream in-frame translation start codon, when compared to variant 2. The encoded protein has a 15 aa longer N-terminus, as compared to isoform 2.
VE:
1 * 100 µl
Preis auf Anfrage
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