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4,5-Dimethylpyridazine-3,6-diol
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4,5-Dimethylpyridazine-3,6-diol
Artikel-Nr:
(SIALBCR153R-10MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
BCR153R-10MG
Lokale Artikelnummer::
SIALBCR153R-10MG
Beschreibung:
Dibenzo[a,h]acridin, Sigma-Aldrich®
VE:
1 * 10 mg
Artikel-Nr:
(SIAL214671-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
214671-5G
Lokale Artikelnummer::
SIAL214671-5G
Beschreibung:
3-Acetylcumarin, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-13492R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13492R-CY5
Lokale Artikelnummer::
BOSSBS-13492R-CY5
Beschreibung:
The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
VE:
1 * 100 µl
Lieferant:
SCHURR SCHUHVERTRIEB
Beschreibung:
Individually designable cleanroom boot made from breathable microfibre upper.
Artikel-Nr:
(BOSSBS-3804R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3804R-A680
Lokale Artikelnummer::
BOSSBS-3804R-A680
Beschreibung:
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and Recognises single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3804R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3804R-A488
Lokale Artikelnummer::
BOSSBS-3804R-A488
Beschreibung:
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL524336-5ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
524336-5ML
Lokale Artikelnummer::
SIAL524336-5ML
Beschreibung:
4-Bromindol, Sigma-Aldrich®
VE:
1 * 5 mL
Artikel-Nr:
(ABCRAB153973.0002)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB153973.0002
Lokale Artikelnummer::
ABCRAB153973.0002
Beschreibung:
3-Aminothiobenzamid
VE:
1 * 2 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
LEICA MICROSYSTEMS
Beschreibung:
Die Mikroskope Leica DM750 wurden speziell entwickelt, um den naturwissenschaftlichen Unterricht zu erleichtern. DM750 ist im Wesentlichen für die vielseitigen Anforderungen fortgeschrittener Kurse in Biowissenschaften und für die Berufsausbildung, beispielsweise an medizinischen, veterinärmedizinischen und zahnmedizinischen Schulen, konzipiert.
Artikel-Nr:
(APOSOR470126-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR470126-25G
Lokale Artikelnummer::
APOSOR470126-25G
Beschreibung:
1,3-Bis(2,4,6-trimethylphenyl)imidazoliumchlorid
VE:
1 * 25 g
Lieferant:
CONTEC
Beschreibung:
SATWIPES® Sigma™ consists of a perforated roll of saturated wipes which are dispensed through a center-pull canister. The wipes are made of 55% cellulose and 45% polyester presaturated with IPA and DI water.
Artikel-Nr:
(635-0240)
Lieferant:
ATAGO
Hersteller-Artikelnummer::
4436
Lokale Artikelnummer::
ATAG4436
Beschreibung:
The PAL series with special scales are pocket instruments delivering rapid results for automotive, aviation, heat transfer and industrial applications.
VE:
1 * 1 ST
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5,7-Bis(trifluoromethyl)-3-cyano-2-(cyanomethyl)pyrazolo[1,5-A]pyrimidine 97%
Lieferant:
Sigma-Aldrich
Beschreibung:
Agarose, Sigma-Aldrich®
Artikel-Nr:
(1380535.)
Lieferant:
USP
Hersteller-Artikelnummer::
1380535
Lokale Artikelnummer::
USPH1380535
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 50 mg
Artikel-Nr:
(1225292.)
Lieferant:
USP
Hersteller-Artikelnummer::
1225292
Lokale Artikelnummer::
USPH1225292
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 20 mg
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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