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4-(Cyanomethyl)-3-fluorobenzene-1-sulphonyl+chloride
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4-(Cyanomethyl)-3-fluorobenzene-1-sulphonyl+chloride
Artikel-Nr:
(BOSSBS-11041R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11041R-CY7
Lokale Artikelnummer::
BOSSBS-11041R-CY7
Beschreibung:
The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE10717982-1KG)
Lieferant:
Molekula
Hersteller-Artikelnummer::
10717982-1KG
Lokale Artikelnummer::
MOLE10717982-1KG
Beschreibung:
Benzyltrimethylammoniumchlorid
VE:
1 * 1 kg
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(SIAL195995-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
195995-25G
Lokale Artikelnummer::
SIAL195995-25G
Beschreibung:
2-Thienylacetylchlorid, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
Spectrum Chemical
Beschreibung:
Aluminiumchlorid Hexahydrat USP
Artikel-Nr:
(FLUO018574-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
018574-5G
Lokale Artikelnummer::
FLUO018574-5G
Beschreibung:
2,5-Dimethoxybenzylchlorid
VE:
1 * 5 g
This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
3-Phenylpropionylchlorid, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Benzolselenylchlorid, Sigma-Aldrich®
Artikel-Nr:
(FLUO018779-10G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
018779-10G
Lokale Artikelnummer::
FLUO018779-10G
Beschreibung:
3-Anisoylchlorid
VE:
1 * 10 g
This is a MarketSource item. Additional charges may apply
Lieferant:
FLUOROCHEM
Beschreibung:
α,α,α-Trifluor-o-toluoylchlorid
Lieferant:
Thermo Scientific
Beschreibung:
2-(Propylthio)nicotinoylchlorid
Lieferant:
FLUOROCHEM
Beschreibung:
3-Methyl-2-thiophencarbonylchlorid
Lieferant:
FLUOROCHEM
Beschreibung:
2-Fluorbenzoylchlorid
Artikel-Nr:
(MOLE22303758-100G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
22303758-100G
Lokale Artikelnummer::
MOLE22303758-100G
Beschreibung:
Tritylchlorid
VE:
1 * 100 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-11041R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11041R-A488
Lokale Artikelnummer::
BOSSBS-11041R-A488
Beschreibung:
The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4176R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4176R
Lokale Artikelnummer::
BOSSBS-4176R
Beschreibung:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE12162979-500G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
12162979-500G
Lokale Artikelnummer::
MOLE12162979-500G
Beschreibung:
1-(2-Chlorethyl)piperidiniumchlorid
VE:
1 * 500 g
This is a MarketSource item. Additional charges may apply
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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