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75 648 results were found
Lithium+sulphide
Artikel-Nr:
(BOSSBS-5425R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5425R-FITC
Lokale Artikelnummer::
BOSSBS-5425R-FITC
Beschreibung:
MAX protein is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0025M-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0025M-A488
Lokale Artikelnummer::
BOSSBS-0025M-A488
Beschreibung:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1;PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Three alternative splice variants of PSEN1 have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0332R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0332R-A750
Lokale Artikelnummer::
BOSSBS-0332R-A750
Beschreibung:
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1398R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1398R-A750
Lokale Artikelnummer::
BOSSBS-1398R-A750
Beschreibung:
Stimulates transcription. Binds to purine-rich DNA sequences. Can form a ternary complex with the serum response factor and the ETS and SRF motifs of the fos serum response element.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15576R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15576R-A680
Lokale Artikelnummer::
BOSSBS-15576R-A680
Beschreibung:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localises to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7954R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7954R-A680
Lokale Artikelnummer::
BOSSBS-7954R-A680
Beschreibung:
Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.Involvement in disease:Defects in ALAD are the cause of acute hepatic porphyria (AHP). AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1506R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1506R-A488
Lokale Artikelnummer::
BOSSBS-1506R-A488
Beschreibung:
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1506R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1506R-A680
Lokale Artikelnummer::
BOSSBS-1506R-A680
Beschreibung:
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5803R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5803R-HRP
Lokale Artikelnummer::
BOSSBS-5803R-HRP
Beschreibung:
Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13340R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13340R-CY7
Lokale Artikelnummer::
BOSSBS-13340R-CY7
Beschreibung:
Members of the mTERF family, including MTERF, MTERFD1, MTERFD2 and MTERFD3, are mitochondrial proteins that are believed to be transcription termination factors. MTERF (mitochondrial transcription termination factor 1) is composed of 399 amino acids and contains three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It has been suggested that only the phosphorylated form of MTERF has transcription termination activity. MTERFD1 is also thought to act as a mitochondrial transcription regulator and is expressed as two isoforms produced by alternative splicing. MTERFD3 is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription. MTERFD3 is expressed in heart, skeletal muscle, pancreas and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13340R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13340R-CY3
Lokale Artikelnummer::
BOSSBS-13340R-CY3
Beschreibung:
Members of the mTERF family, including MTERF, MTERFD1, MTERFD2 and MTERFD3, are mitochondrial proteins that are believed to be transcription termination factors. MTERF (mitochondrial transcription termination factor 1) is composed of 399 amino acids and contains three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It has been suggested that only the phosphorylated form of MTERF has transcription termination activity. MTERFD1 is also thought to act as a mitochondrial transcription regulator and is expressed as two isoforms produced by alternative splicing. MTERFD3 is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription. MTERFD3 is expressed in heart, skeletal muscle, pancreas and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2305R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2305R-CY3
Lokale Artikelnummer::
BOSSBS-2305R-CY3
Beschreibung:
E2 EPF is a member of the ubiquitin conjugating enzyme family. It is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme dependent manner, a characteristic property of ubiquitin carrier proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7799R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7799R
Lokale Artikelnummer::
BOSSBS-7799R
Beschreibung:
The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15088R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15088R-CY3
Lokale Artikelnummer::
BOSSBS-15088R-CY3
Beschreibung:
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8376R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8376R-CY3
Lokale Artikelnummer::
BOSSBS-8376R-CY3
Beschreibung:
RNF160 may function as an E3 ubiquitin-protein ligase. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4562R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4562R-A488
Lokale Artikelnummer::
BOSSBS-4562R-A488
Beschreibung:
Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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