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(4-Isopropylphenoxy)acetyl+chloride
Artikel-Nr:
(BOSSBS-13686R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13686R-A488
Lokale Artikelnummer::
BOSSBS-13686R-A488
Beschreibung:
MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13686R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13686R-A647
Lokale Artikelnummer::
BOSSBS-13686R-A647
Beschreibung:
MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0251R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0251R-A488
Lokale Artikelnummer::
BOSSBS-0251R-A488
Beschreibung:
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0251R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0251R-A555
Lokale Artikelnummer::
BOSSBS-0251R-A555
Beschreibung:
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
VE:
1 * 100 µl
Artikel-Nr:
(85739.290)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC85739.290
Beschreibung:
The reagent is specially intended for use in testing Ph Eur and monographs. This solution was produced according 4.1.1 of Ph Eur specifications using Ph Eur reagent quality components and water meeting the Ph Eur monograph requirement for purified water.
VE:
1 * 1 L
Lieferant:
Alfa Aesar
Beschreibung:
4-(Trifluormethyl)benzolsulfonylchlorid ≥98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Brom-1,5-dimethyl-1H-pyrazol-3-carbonylchlorid
Lieferant:
Thermo Scientific
Beschreibung:
p-Tolylhydraziniumchlorid 98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Ethoxyacryloylchlorid 90%
Lieferant:
Thermo Scientific
Beschreibung:
Diethylaluminiumchlorid 1 M in Hexanen, AcroSeal™
Lieferant:
Alfa Aesar
Beschreibung:
Pirenzepine dihydrochloride 99%
Lieferant:
Alfa Aesar
Beschreibung:
3-Phenoxybenzylchlorid ≥97%
Lieferant:
Alfa Aesar
Beschreibung:
Benzyldimethylhexadecylammonium chloride has been used in a study to assess the removal of cationic surfactants from aqueous solutions using activated carbon cloth (ACC). It has also been used in a study to investigate the prototropic behavior of the dye, 7-hydroxy-4-methylcoumarin (7H4MC).
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Chlor-3-fluorbenzoylchlorid 97%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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