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4-Chloro-2-methylbenzofuro[3,2-d]pyrimidine
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4-Chloro-2-methylbenzofuro[3,2-d]pyrimidine
Artikel-Nr:
(SIALI6875-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
I6875-5G
Lokale Artikelnummer::
SIALI6875-5G
Beschreibung:
5-Iodcytosin, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-11684R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11684R-A488
Lokale Artikelnummer::
BOSSBS-11684R-A488
Beschreibung:
Puromycin-sensitive aminopeptidase is a 100kDa zinc metallopeptidase which degrades neuropeptides by removing amino acid residues from the amino-terminus. The protein is the most abundant aminopeptidase in the brain, however it is not exclusive to that organ. It is localized primarily in the cytoplasm, and plays a role in the metabolism of neuropeptides in nerve terminals and synaptic clefts. The human PSA gene maps to chromosome 17q 2-32.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11684R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11684R-FITC
Lokale Artikelnummer::
BOSSBS-11684R-FITC
Beschreibung:
Puromycin-sensitive aminopeptidase is a 100kDa zinc metallopeptidase which degrades neuropeptides by removing amino acid residues from the amino-terminus. The protein is the most abundant aminopeptidase in the brain, however it is not exclusive to that organ. It is localized primarily in the cytoplasm, and plays a role in the metabolism of neuropeptides in nerve terminals and synaptic clefts. The human PSA gene maps to chromosome 17q 2-32.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-190)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-190
Lokale Artikelnummer::
PRSI91-190
Beschreibung:
beta -Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily. beta -Ureidopropionase binds one zinc ion per subunit, catalyzes the last step in the pyrimidine degradation pathway. beta -Ureidopropionase can convert N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide, respectively. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta aminoisobutyric acid, respectively. Defects in beta -Ureidopropionase are the cause of beta -Ureidopropionase deficiency that is characterized by muscular hypotonia, dystonic movements, scoliosis, microcephaly and severe developmental delay.
VE:
1 * 50 µG
Lieferant:
Alfa Aesar
Beschreibung:
Titan ≥99,7% (Metall-Basis), Drahtform, geglüht, Länge 90 cm (35 in), Ø 0.81 mm (0.032 in)
Artikel-Nr:
(BLDPBD491148-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD491148-25G
Lokale Artikelnummer::
BLDPBD491148-25G
Beschreibung:
1-Decyl-3-methylimidazoliumbromid 98%
VE:
1 * 25 g
Artikel-Nr:
(22525.296)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC22525.296
Beschreibung:
Carboxymethylcellulose Natriumsalz, TECHNICAL, mittlere Viskosität
VE:
1 * 1 kg
Lieferant:
Thermo Scientific
Beschreibung:
Pyridino[3,2-b]pyrazin
Lieferant:
Sigma-Aldrich
Beschreibung:
2'-Deoxyuridin, Sigma-Aldrich®
Lieferant:
MP Biomedicals
Beschreibung:
Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the 2' position.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Peptide antibiotic.
Lieferant:
BLD PHARMATECH GMBH
Beschreibung:
4-Fluoro-2-hydroxybenzeneboronic acid pinacol ester 97%
Lieferant:
COMBI-BLOCKS
Beschreibung:
5-Brom-4-hexylpyrimidin
Artikel-Nr:
(BOSSBS-8288R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8288R-CY5.5
Lokale Artikelnummer::
BOSSBS-8288R-CY5.5
Beschreibung:
Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8288R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8288R-A488
Lokale Artikelnummer::
BOSSBS-8288R-A488
Beschreibung:
Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
5-Bromuridin, Sigma-Aldrich®
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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