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4-Chloro-5-fluoro-2-methoxypyrimidine
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4-Chloro-5-fluoro-2-methoxypyrimidine
Artikel-Nr:
(PRSI7249P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7249P
Lokale Artikelnummer::
PRSI7249P
Beschreibung:
16 amino acid peptide near the carboxy terminus of human RRAS2.
VE:
1 * 50 µG
Artikel-Nr:
(ABNOMAB14711)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB14711
Lokale Artikelnummer::
ABNOMAB14711
Beschreibung:
Mouse monoclonal antibody raised against human testosterone.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7263P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7263P
Lokale Artikelnummer::
PRSI7263P
Beschreibung:
15 amino acids near the carboxy terminus of human KREMEN2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7391P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7391P
Lokale Artikelnummer::
PRSI7391P
Beschreibung:
19 amino acids near the carboxy terminus of human AKT1S1.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4415P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4415P
Lokale Artikelnummer::
PRSI4415P
Beschreibung:
19 amino acids near the carboxy terminus of human TBC1D4.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4445P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4445P
Lokale Artikelnummer::
PRSI4445P
Beschreibung:
16 amino acids near the carboxy terminus of human RIM2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7289P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7289P
Lokale Artikelnummer::
PRSI7289P
Beschreibung:
15 amino acids near the carboxy terminus of human ERRF2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7309P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7309P
Lokale Artikelnummer::
PRSI7309P
Beschreibung:
16 amino acids near the carboxy terminus of human KANK2.
VE:
1 * 50 µG
Artikel-Nr:
(BNUM0498-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0498-50
Lokale Artikelnummer::
BTIUBNUM0498-50
Beschreibung:
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
VE:
1 * 50 µl
Artikel-Nr:
(BTIUBNUM1166-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1166-50
Lokale Artikelnummer::
BTIUBNUM1166-50
Beschreibung:
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-13031R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13031R-A488
Lokale Artikelnummer::
BOSSBS-13031R-A488
Beschreibung:
ARID3A, also known as DRIL1 in humans and Bright (for B cell regulator of IgH transcription) in mice, are the mammalian homologs of the Drosophila Dri (dead ringer) protein. ARID3A is developmentally regulated and is expressed in a restricted set of cells, including differentiating cells of the gut and salivary glands. ARID3A represents a member of a unique family of transcriptional activators that shares sequence similarity to proteins of SWI/SNF complexes; it contains an A/T-rich DNA-binding (ARID) domain and a distinct domain involved in tetramerization. The gene encoding ARID3A is linked to a marker of Peutz-Jeghers syndrome, which is an autosomal-dominant disorder characterized by melanocytic macules of the lips, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, including gastrointestinal cancer. E2FBP1 (E2F-1 binding protein 1) is identical to ARID3A in the carboxy terminal region. E2FBP1 appears to lack DNA binding and transactivation domains, and it functions to regulate the transcription of proteins involved in cell proliferation by binding to the transcription factor E2F-1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13031R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13031R-A555
Lokale Artikelnummer::
BOSSBS-13031R-A555
Beschreibung:
ARID3A, also known as DRIL1 in humans and Bright (for B cell regulator of IgH transcription) in mice, are the mammalian homologs of the Drosophila Dri (dead ringer) protein. ARID3A is developmentally regulated and is expressed in a restricted set of cells, including differentiating cells of the gut and salivary glands. ARID3A represents a member of a unique family of transcriptional activators that shares sequence similarity to proteins of SWI/SNF complexes; it contains an A/T-rich DNA-binding (ARID) domain and a distinct domain involved in tetramerization. The gene encoding ARID3A is linked to a marker of Peutz-Jeghers syndrome, which is an autosomal-dominant disorder characterized by melanocytic macules of the lips, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, including gastrointestinal cancer. E2FBP1 (E2F-1 binding protein 1) is identical to ARID3A in the carboxy terminal region. E2FBP1 appears to lack DNA binding and transactivation domains, and it functions to regulate the transcription of proteins involved in cell proliferation by binding to the transcription factor E2F-1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13031R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13031R-CY3
Lokale Artikelnummer::
BOSSBS-13031R-CY3
Beschreibung:
ARID3A, also known as DRIL1 in humans and Bright (for B cell regulator of IgH transcription) in mice, are the mammalian homologs of the Drosophila Dri (dead ringer) protein. ARID3A is developmentally regulated and is expressed in a restricted set of cells, including differentiating cells of the gut and salivary glands. ARID3A represents a member of a unique family of transcriptional activators that shares sequence similarity to proteins of SWI/SNF complexes; it contains an A/T-rich DNA-binding (ARID) domain and a distinct domain involved in tetramerization. The gene encoding ARID3A is linked to a marker of Peutz-Jeghers syndrome, which is an autosomal-dominant disorder characterized by melanocytic macules of the lips, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, including gastrointestinal cancer. E2FBP1 (E2F-1 binding protein 1) is identical to ARID3A in the carboxy terminal region. E2FBP1 appears to lack DNA binding and transactivation domains, and it functions to regulate the transcription of proteins involved in cell proliferation by binding to the transcription factor E2F-1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11041R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11041R-A350
Lokale Artikelnummer::
BOSSBS-11041R-A350
Beschreibung:
The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5193R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5193R-A647
Lokale Artikelnummer::
BOSSBS-5193R-A647
Beschreibung:
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6954R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6954R
Lokale Artikelnummer::
BOSSBS-6954R
Beschreibung:
Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB which is activated as a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein). These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. p300 molecules lacking an intact E1A binding site bypass E1A repression even in the presence of high concentrations of E1A. Sequence analysis of CBP and p300 has revealed substantial homology, arguing that these proteins are members of a conserved family of co-activators.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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