4-Fluoro-3-methylpyridin-2-amine
Lieferant:
Avantor
Beschreibung:
BAKERBOND spe™ Säulen für den Einmalgebrauch aus PP, vorgefüllt mit hochkapazitiven Sorbentien zwischen zwei 20-µm-PE-Fritten.
Artikel-Nr:
(J64468.03)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J64468.03
Lokale Artikelnummer::
ALFAJ64468.03
Beschreibung:
2-Amino-6-chloropurine riboside 95%
VE:
1 * 1 g
Artikel-Nr:
(PRSI30-425)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-425
Lokale Artikelnummer::
PRSI30-425
Beschreibung:
TYMS catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-47 CR601528.1 1-47 48-1099 X02308.1 14-1065 1100-1603 BC083512.1 1067-1570
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3761)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3761
Lokale Artikelnummer::
PRSI3761
Beschreibung:
LSD1 Antibody: Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is a recently discovered amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues (such as H3-K4) is associated with active transcription. LSD1 associates with various proteins, including HDAC1/2, CoREST, and BHC80, that act to regulate LSD1 activity in vivo, and in a histone H3-K4-specific methylase complex that is involved in transcriptional regulation. Experiments have shown that CoREST, a SANT domain-containing corepressor acts to enhance LSD1 activity, while BHC80, a PHD domain-containing protein, inhibits CoREST/LSD1 activity in vitro. LSD1-mediated histone demethylation thus may have significant effects on gene expression.
VE:
1 * 100 µG
Artikel-Nr:
(HEWL5982-5258CH)
Lieferant:
Agilent
Hersteller-Artikelnummer::
5982-5258CH
Lokale Artikelnummer::
HEWL5982-5258CH
Beschreibung:
<B>Stufe 2: Dispersive SPE-Reinigung</B>Wählen Sie das zerstreuend SPE-Kit, das für die Art der zu analysierenden Lebensmittel und die von Ihnen angewandte Methode geeignet ist. In diesem Schritt wird ein Aliquot des Probenextrakts aus Schritt eins (siehe QuEChERS-Extraktionskits) in ein 2- oder 15-ml-Zentrifugenröhrchen gegeben, das eine kleine Menge SPE-Sorbens und MgSO₄ enthält. Das Sorbens zieht störende Matrixmaterialien aus der Probe heraus, während das MgSO₄ dabei hilft, überschüssiges Wasser zu entfernen und die Analytverteilung zu verbessern.
VE:
1 * 1 ST
Artikel-Nr:
(PRSI3763)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3763
Lokale Artikelnummer::
PRSI3763
Beschreibung:
LSD1 Antibody: Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is a recently discovered amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues (such as H3-K4) is associated with active transcription. LSD1 associates with various proteins, including HDAC1/2, CoREST, and BHC80, that act to regulate LSD1 activity in vivo, and in a histone H3-K4-specific methylase complex that is involved in transcriptional regulation. Experiments have shown that CoREST, a SANT domain-containing corepressor acts to enhance LSD1 activity, while BHC80, a PHD domain-containing protein, inhibits CoREST/LSD1 activity in vitro. LSD1-mediated histone demethylation thus may have significant effects on gene expression.
VE:
1 * 100 µG
Lieferant:
FLUOROCHEM
Beschreibung:
(±)-2-Fluormandelsäure
Lieferant:
VWR Chemicals
Beschreibung:
Yeast Nitrogen Base (YNB) is a base medium for preparation of minimal and synthetic defined yeast media.
Lieferant:
FLUOROCHEM
Beschreibung:
(±)-4-Fluormandelsäure
Lieferant:
MP Biomedicals
Beschreibung:
FOA is a derivative of a pyrimidine precursor and is selectively toxic to yeast cells which synthesize orotidine-5’-phosphate decarboxylase. FOA has been used in a positive selection for uracil-requiring mutants(in the presence of large numbers of wild-type cells) lacking OMPdecase or OPRTase activities. This results in efficient strains for effective transformation systems.
Lieferant:
Sigma-Aldrich
Beschreibung:
2-Aminobenzylamin, Sigma-Aldrich®
Lieferant:
MP Biomedicals
Beschreibung:
Storage: Store at +4 °C, store under nitrogen
Glutathione is the major low molecular weight thiol compound of the living plant or animal cell. It is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. The sulfhydryl (thiol) group (SH) of cysteine serves as a proton donor and is responsible for the biological activity of glutathione. Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
Lieferant:
GE Healthcare - Whatman
Beschreibung:
These filter papers can be used for the absorption of culture media, as a blotting paper, for electrophoresis and amino acid chromatography.
Lieferant:
Sigma-Aldrich
Beschreibung:
4-Aminobenzylamin, Sigma-Aldrich®
Artikel-Nr:
(SIAL721492-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
721492-5G
Lokale Artikelnummer::
SIAL721492-5G
Beschreibung:
3-Aminobenzylamin, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Naphthol yellow S has been used as a staining agent in fixed human embryonic stem cell-derived cardiomyocytes.
Preis auf Anfrage
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