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Tetrabutylazanium+trifluoro(3-methoxyphenyl)boranuide
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Tetrabutylazanium+trifluoro(3-methoxyphenyl)boranuide
Artikel-Nr:
(MOLE16255417-5G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
16255417-5G
Lokale Artikelnummer::
MOLE16255417-5G
Beschreibung:
12-Krone-4 (1,4,7,10-Tetraoxacyclododecan, Lithium-Ionophor V)
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-12210R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12210R-CY3
Lokale Artikelnummer::
BOSSBS-12210R-CY3
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF81, also known as HFZ20 or MRX45, is a transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. It localizes to the nucleus and contains 12 C2H2-type zinc fingers and 1 KRAB domain. Mutations in the gene encoding ZNF81 are implicated in nonsyndromic X-linked mental retardation (XLMR).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5373R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5373R-A488
Lokale Artikelnummer::
BOSSBS-5373R-A488
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5372R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5372R-CY5.5
Lokale Artikelnummer::
BOSSBS-5372R-CY5.5
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3303R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3303R
Lokale Artikelnummer::
BOSSBS-3303R
Beschreibung:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3322R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3322R-CY5.5
Lokale Artikelnummer::
BOSSBS-3322R-CY5.5
Beschreibung:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11271R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11271R-CY3
Lokale Artikelnummer::
BOSSBS-11271R-CY3
Beschreibung:
Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0426-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0426-50
Lokale Artikelnummer::
BTIUBNUM0426-50
Beschreibung:
Recognizes a 12-14 kDa doublet of Calgranulin A/B (also known as S100A8/A9 or MRP-8/14); expressed by granulocytes, monocytes and by tissue macrophages.The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-8346R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8346R-CY5
Lokale Artikelnummer::
BOSSBS-8346R-CY5
Beschreibung:
FGFR1OP2 belongs to the SIKE family. The FGFR1OP2 (FGFR1 oncogene partner 2) gene was identified through its involvement in a fusion with the FGFR1 gene. FGFR1OP2 may be involved in the wound healing pathway. It is expressed in bone marrow, spleen and thymus. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T cell or B cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12303R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12303R-CY5
Lokale Artikelnummer::
BOSSBS-12303R-CY5
Beschreibung:
Hemogen is a 484 amino acid protein encoded by the human gene HEMGN. Hemogen is a nuclear protein that is expressed in hematopoietic precursor cells and can be detected in CD34+ and K-562 leukemia cell line. It is also expressed in bone marrow, testis, thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. Hemogen is down-regulated during megakaryocytic differentiation of K-562 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) (at protein level). It can be up-regulated in normal PBMCs by mitogens.
VE:
1 * 100 µl
Artikel-Nr:
(473281000.)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
473281000
Lokale Artikelnummer::
ACRO473281000
Beschreibung:
1,2-Distearoyl-sn-glycero-3-phosphocholine 95%
VE:
1 * 100 mg
New Product
Lieferant:
Alfa Aesar
Beschreibung:
Dithiothreitol (DTT, Cleland's Reagenz) ≥98%
Lieferant:
Biotium
Beschreibung:
This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
Lieferant:
Sigma-Aldrich
Beschreibung:
3,4-Dihydroxy-3-cyclobuten-1,2-dion, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
Bromphenolblau Natriumsalz, wasserlöslich, rein Indikator
Artikel-Nr:
(BLDPBD129758-500G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD129758-500G
Lokale Artikelnummer::
BLDPBD129758-500G
Beschreibung:
EDTA Trikaliumsalz 98+%
VE:
1 * 500 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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