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3-Bromo-6-chloro-2-fluorobenzoic+acid
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3-Bromo-6-chloro-2-fluorobenzoic+acid
Artikel-Nr:
(PRSI30-292)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-292
Lokale Artikelnummer::
PRSI30-292
Beschreibung:
Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. ARGFX gene is a member of the ARGFX homeobox gene family.Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the ARGFX homeobox gene family.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-311)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-311
Lokale Artikelnummer::
PRSI45-311
Beschreibung:
Anti-EIF3M Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-199)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-199
Lokale Artikelnummer::
PRSI92-199
Beschreibung:
UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyses the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-254)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-254
Lokale Artikelnummer::
PRSI45-254
Beschreibung:
Anti-ANLN Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXP-5291)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5291
Lokale Artikelnummer::
PRSIXP-5291
Beschreibung:
Anti-VEGFA Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-730)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-730
Lokale Artikelnummer::
PRSI79-730
Beschreibung:
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex act via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-525)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-525
Lokale Artikelnummer::
PRSI79-525
Beschreibung:
Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXPS-1020)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XPS-1020
Lokale Artikelnummer::
PRSIXPS-1020
Beschreibung:
The three Mitogen-Activated Protein Kinases (MAPKs) are evolutionarily conserved protein kinases that control a vast array of cellular processes. p38 MAPK is one these kinases and it is activated by both inflammatory cytokines and by stress. The p38 MAPK is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI79-558)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-558
Lokale Artikelnummer::
PRSI79-558
Beschreibung:
ATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI50-269)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
50-269
Lokale Artikelnummer::
PRSI50-269
Beschreibung:
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gamma;s, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma-subunit is required for benzodiazepine modulation. It has recently been suggested that PKCepsilon regulates the sensitivity of GABAA alpha1beta2gamma2 receptors to ethanol and benzodiazepines through phosphorylation of serine 327 in the large intracellular loop of gamma2 (Qi et al., 2007)
VE:
1 * 100 µl
Artikel-Nr:
(PRSI79-504)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-504
Lokale Artikelnummer::
PRSI79-504
Beschreibung:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells By similarity. Phosphorylates heat shock factor protein 4 (HSF4). /Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it./Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. Required for stress-induced neuronal apoptosis and the pathogenesis of glutamate excitotoxicity
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5655)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5655
Lokale Artikelnummer::
PRSI5655
Beschreibung:
EFHD1 Antibody: EFHD1, also known as Swiprosin-2 or SWS2, is an EF-hand and coiled-coil-containing adaptor protein identified in a subtractive hybridization study using a neuronal cell line established from the cerebellum of an adult p53-null mouse, however further study indicated no difference in normal mice. Its mRNA is widely expressed, with its expression in brain undetectable at embryonic stages, with increasing levels from postnatal to adult development. In situ hybridization showed expression in neurons but not white matter of the cerebellum and cerebrum. EHFD1 is also highly expressed in testes, ovary, and the collecting ducts of the kidney, suggesting that in non-neuronal cells, EFHD1 may be involved in gametogenesis and water-reabsorbtion.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI23-499)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-499
Lokale Artikelnummer::
PRSI23-499
Beschreibung:
Anti-OPRK1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI24-808)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-808
Lokale Artikelnummer::
PRSI24-808
Beschreibung:
Anti-S Recombinant Antibody [Clone: CR3022]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI42-501)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-501
Lokale Artikelnummer::
PRSI42-501
Beschreibung:
Anti-PDE1A Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI23-491)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-491
Lokale Artikelnummer::
PRSI23-491
Beschreibung:
Anti-IFNL1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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