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5,5'-Dibrom-2,2'-bithiophen
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5,5'-Dibrom-2,2'-bithiophen
Artikel-Nr:
(PRSI91-037)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-037
Lokale Artikelnummer::
PRSI91-037
Beschreibung:
Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R beta (previously known as CRF2-4), belonging to the class II cytokine receptor family.
VE:
1 * 50 µG
Artikel-Nr:
(MOLEM59166281)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M59166281
Lokale Artikelnummer::
MOLEM59166281
Beschreibung:
Nitrilotriessigsäure
VE:
1 * 500 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(36893-2ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
36893-2ML
Lokale Artikelnummer::
SUPL36893-2ML
Beschreibung:
Organic Standard, trans-Permethrin 10 µg/ml in Cyclohexan, Packung: Glasflasche
VE:
1 * 2 mL
Artikel-Nr:
(EDQMY0001233)
Lieferant:
EDQM
Hersteller-Artikelnummer::
Y0001233
Lokale Artikelnummer::
EDQMY0001233
Beschreibung:
Organic Standard, Fosinopril impurity K, (2S,4S)-4-cyclohexyl-1-(2,2-dimethyl-1-oxopropyl)pyrrolidine-2-carboxylic acid, Ph. Eur. standard
VE:
1 * 5 mg
Artikel-Nr:
(BLEG408305)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
408305
Lokale Artikelnummer::
BLEG408305
Beschreibung:
Anti-FITC Mouse Monoclonal Antibody [clone: FIT-22]
VE:
1 * 100 µG
This is a MarketSource item. Additional charges may apply
Lieferant:
SOCOREX ISBA
Beschreibung:
Blunt end cannulas provide precise distribution with Luer nozzle microdispensers.
Artikel-Nr:
(412-1164)
Lieferant:
IKA
Hersteller-Artikelnummer::
0521800
Lokale Artikelnummer::
IKAA0521800
Beschreibung:
Hartmetallschläger M 22, Für: Zum Zerschlagen von Substanzen bis Mohshärte 9, Für: M 20 Universal Mill
VE:
1 * 1 ST
Lieferant:
SOCOREX ISBA
Beschreibung:
Flaschenhalsadapter, mit Gewinde, PP, Außen-Ø 22 mm, Calibrex™
Artikel-Nr:
(BOSSBS-12495R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-A488
Lokale Artikelnummer::
BOSSBS-12495R-A488
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-HRP
Lokale Artikelnummer::
BOSSBS-13343R-HRP
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI24-316)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-316
Lokale Artikelnummer::
PRSI24-316
Beschreibung:
Anti-BCL5 Recombinant Antibody [Clone: SAIC-23B-22]
VE:
1 * 0,2 mg
New Product
Lieferant:
Sigma-Aldrich
Beschreibung:
Thiodiglycol, Sigma-Aldrich®
Lieferant:
Alfa Aesar
Beschreibung:
Diethylether, wasserfrei ≥99% stabilisiert ACS
Artikel-Nr:
(BOSSBS-9748R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R-CY7
Lokale Artikelnummer::
BOSSBS-9748R-CY7
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9748R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R-CY5
Lokale Artikelnummer::
BOSSBS-9748R-CY5
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(PROOCIL-PCB-201)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-201
Lokale Artikelnummer::
PROOCIL-PCB-201
Beschreibung:
Organic Standard, 2,2',3,3',4,5,5',6'-Octachlorbiphenyl (PCB Nr. 201) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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