5,5'-Dibrom-2,2'-bithiophen
Artikel-Nr:
(PROOMM0172.00)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0172.00
Lokale Artikelnummer::
PROOMM0172.00
Beschreibung:
L(-)-Tryptophan
VE:
1 * 500 mg
Artikel-Nr:
(462-0045)
Lieferant:
NICKEL ELECTRO
Hersteller-Artikelnummer::
NE4-22D
Lokale Artikelnummer::
NICKNE4-22D
Beschreibung:
General purpose stirred water baths offering good temperature stability and uniformity for consistent, repeatable results. Operation below ambient is possible using an optional refrigerated dip cooler.
VE:
1 * 1 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
Ricinoleic acid ≥99% (durch GC), Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
2,6-Di-tert-butyl-p-benzochinon, Sigma-Aldrich®
Artikel-Nr:
(ENAMEN30002005.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN30002005.1G
Lokale Artikelnummer::
ENAMEN30002005.1G
Beschreibung:
4,5-Dichlor-3(2H)-pyridazinon
VE:
1 * 1 g
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Lieferant:
Alfa Aesar
Beschreibung:
Silber 0,02 mg/ml ausgeliefert in 2 mM Natriumcitrat, Nanopartikel 20 nm (Abs. 405 nm)
Artikel-Nr:
(ENAMEN30008055.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN30008055.1G
Lokale Artikelnummer::
ENAMEN30008055.1G
Beschreibung:
1-(2,3-Xylyl)piperazin
VE:
1 * 1 g
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Artikel-Nr:
(BOSSBS-1865R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1865R-A555
Lokale Artikelnummer::
BOSSBS-1865R-A555
Beschreibung:
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM2, USP3, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or detoxification of abnormally folded or damaged protein by mediating 'Lys-63'-linked polyubiquitination of misfolded proteins such as PARK7: 'Lys-63'-linked polyubiquitinated misfolded proteins are then recognized by HDAC6, leading to their recruitment to aggresomes, followed by degradation. Mediates 'Lys-63'-linked polyubiquitination of SNCAIP, possibly playing a role in Lewy-body formation. Mediates monoubiquitination of BCL2, thereby acting as a positive regulator of autophagy. Promotes the autophagic degradation of dysfunctional depolarized mitochondria (mitophagy) by the ubiquitination of mitochondrial proteins such as TOMM2, RHOT1/MIRO1 and USP3 (PubMed:24896179). Mediates 'Lys-48'-linked polyubiquitination of ZNF746, followed by degradation of ZNF746 by the proteasome; possibly playing a role in the regulation of neuron death. Limits the production of reactive oxygen species (ROS). Regulates cyclin-E during neuronal apoptosis. In collaboration with CHPF isoform 2, may enhance cell viability and protect cells from oxidative stress. Independently of its ubiquitin ligase activity, protects from apoptosis by the transcriptional repression of p53/TP53. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. May represent a tumor suppressor gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1865R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1865R-A647
Lokale Artikelnummer::
BOSSBS-1865R-A647
Beschreibung:
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM2, USP3, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or detoxification of abnormally folded or damaged protein by mediating 'Lys-63'-linked polyubiquitination of misfolded proteins such as PARK7: 'Lys-63'-linked polyubiquitinated misfolded proteins are then recognized by HDAC6, leading to their recruitment to aggresomes, followed by degradation. Mediates 'Lys-63'-linked polyubiquitination of SNCAIP, possibly playing a role in Lewy-body formation. Mediates monoubiquitination of BCL2, thereby acting as a positive regulator of autophagy. Promotes the autophagic degradation of dysfunctional depolarized mitochondria (mitophagy) by the ubiquitination of mitochondrial proteins such as TOMM2, RHOT1/MIRO1 and USP3 (PubMed:24896179). Mediates 'Lys-48'-linked polyubiquitination of ZNF746, followed by degradation of ZNF746 by the proteasome; possibly playing a role in the regulation of neuron death. Limits the production of reactive oxygen species (ROS). Regulates cyclin-E during neuronal apoptosis. In collaboration with CHPF isoform 2, may enhance cell viability and protect cells from oxidative stress. Independently of its ubiquitin ligase activity, protects from apoptosis by the transcriptional repression of p53/TP53. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. May represent a tumor suppressor gene.
VE:
1 * 100 µl
Lieferant:
MICROSOLV
Beschreibung:
Using proprietary bonding technology, the straight chain C18 hydrocarbon is bonded directly to the TYPE-C silica-hydride surface at two separate points of attachment with direct siliconcarbon bonds. This Si-C bond is virtually indestructible and confers great stability and longevity to these columns.
Artikel-Nr:
(548-3057)
Lieferant:
LA PHA PACK
Hersteller-Artikelnummer::
20090342
Lokale Artikelnummer::
LAPH20090342
Beschreibung:
Klare- und braune Glasfläschchen mit gerundetem oder flachem Boden und Volumina von 5 bis 20 ml und Verschlüsse. Fläschchen mit gerundetem Boden zeichnen sich während des Heizvorgangs durch höhere Robustheit und Druckbeständigkeit aus. Fläschchen mit flachem Boden eignen sich besser für bestimmte Laborgeräte.
VE:
1 * 100 ST
Artikel-Nr:
(517301-10)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
517301-10
Lokale Artikelnummer::
CALB517301-10
Beschreibung:
The P-Glycoprotein Inhibitor, C-4 controls the biological activity of P-Glycoprotein. This small molecule/inhibitor is primarily used for Cancer applications.
VE:
1 * 10 mg
Lieferant:
Thermo Fisher Scientific
Beschreibung:
These reversed phase columns were developed in conjunction with the Vanquish™ UHPLC system to take advantage of the system's extended pressure capabilities and robustness. The result is a new level of separation, speed and throughput that solve analytical challenges in liquid chromatography and LC-MS analyses.
Artikel-Nr:
(VARI12162054B)
Lieferant:
VARIAN
Hersteller-Artikelnummer::
12162054B
Lokale Artikelnummer::
VARI12162054B
Beschreibung:
Bond Elut™ Jr cartridges have top and bottom Luer fittings allowing easy sample processing when used in conjunction with standard SPE cartridges. Bond Elut™ LRC cartridges have a large reservoir above the sorbent bed and are suitable for use on any standard SPE vacuum manifold.
VE:
1 * 100 ST
Lieferant:
COMBI-BLOCKS
Beschreibung:
3-Brom-7-chlor-4-hydroxy-8-methyl-2-(trifluormethyl)chinolin
Preis auf Anfrage
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