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Artikel-Nr:
(BOSSBS-5814R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5814R-A750
Lokale Artikelnummer::
BOSSBS-5814R-A750
Beschreibung:
Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organisation is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
VE:
1 * 100 µl
Lieferant:
Portwest Clothing
Beschreibung:
Diese Hose hat ein stilvolles Unisex-Design für multifunktionalen Einsatz, Komfort und ein Hahnentrittmuster. Der halbelastische Bund sorgt für guten Sitz, in den Seiten- und der Gesäßtasche lassen sich Ihre persönlichen Dinge gut verstauen.
Artikel-Nr:
(USBI042180)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042180
Lokale Artikelnummer::
USBI042180
Beschreibung:
Anti-SP1 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(EHERL15990200CY)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
L15990200CY
Lokale Artikelnummer::
EHERL15990200CY
Beschreibung:
Organic Standard, trans-Permethrin 10 µg/ml in Cyclohexan, Packung: Glasflasche
VE:
1 * 10 mL
Artikel-Nr:
(EHERXA15990200CY)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
XA15990200CY
Lokale Artikelnummer::
EHERXA15990200CY
Beschreibung:
Organic Standard, trans-Permethrin 100 µg/ml in Cyclohexan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(EHERL11202000CY)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
L11202000CY
Lokale Artikelnummer::
EHERL11202000CY
Beschreibung:
Organic Standard, trans-Chlordan 10 µg/ml in Cyclohexan, Packung: Glasflasche
VE:
1 * 10 mL
Artikel-Nr:
(BNUM0638-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0638-50
Lokale Artikelnummer::
BTIUBNUM0638-50
Beschreibung:
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-11242R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11242R-A647
Lokale Artikelnummer::
BOSSBS-11242R-A647
Beschreibung:
Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5814R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5814R-HRP
Lokale Artikelnummer::
BOSSBS-5814R-HRP
Beschreibung:
Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A488
Lokale Artikelnummer::
BOSSBS-11333R-A488
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A647
Lokale Artikelnummer::
BOSSBS-11333R-A647
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A555
Lokale Artikelnummer::
BOSSBS-11333R-A555
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A350
Lokale Artikelnummer::
BOSSBS-11333R-A350
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-FITC
Lokale Artikelnummer::
BOSSBS-11333R-FITC
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0887-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0887-50
Lokale Artikelnummer::
BTIUBNUM0887-50
Beschreibung:
Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.
VE:
1 * 50 µl
Artikel-Nr:
(432-0012)
Lieferant:
INTERSCIENCE
Hersteller-Artikelnummer::
251091
Lokale Artikelnummer::
INSC251091
Beschreibung:
BagPipet® ist eine autoklavierbare Pipette mit drei wählbaren Volumen (0,1 ml / 0,9 ml / 1 ml). Zur Nutzung mit BagTips®, einer sterilen und robusten Einwegspitze, die bis auf den Boden der Bags reicht.
VE:
1 * 1 ST
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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