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5-Amino-2-fluor-3-methylpyridin
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5-Amino-2-fluor-3-methylpyridin
Artikel-Nr:
(BOSSBS-13323R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13323R-A488
Lokale Artikelnummer::
BOSSBS-13323R-A488
Beschreibung:
GCSH is a 173 amino acid mitochondrial protein that contains one lipoyl-binding domain and belongs to the gcvH family. Defects in the gene encoding GCSH are the cause of glycine encephalopathy (GCE), an autosomal recessive disease that is also referred to as non-ketotic hyperglycinemia (NKH). Characterized by severe neurological symptoms, patients with GCE have a large amount of glycine accumulated in their body fluids. The gene encoding GCSH maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13323R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13323R-A647
Lokale Artikelnummer::
BOSSBS-13323R-A647
Beschreibung:
GCSH is a 173 amino acid mitochondrial protein that contains one lipoyl-binding domain and belongs to the gcvH family. Defects in the gene encoding GCSH are the cause of glycine encephalopathy (GCE), an autosomal recessive disease that is also referred to as non-ketotic hyperglycinemia (NKH). Characterized by severe neurological symptoms, patients with GCE have a large amount of glycine accumulated in their body fluids. The gene encoding GCSH maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11649R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11649R-A555
Lokale Artikelnummer::
BOSSBS-11649R-A555
Beschreibung:
The NGG1 interacting factor 3-like 1 (NIF3L1) is a 377 amino acid protein expressed mainly in the cytoplasm of cells in several different tissues. It has been highly conserved throughout evolution, from bacteria to mammals. NIF3L participates in retinoic acid-primed neural differentiation of P19 embryonic carcinoma cells by cooperating with Trip15/CSN2, a transcriptional corepressor/component of COP9 signalosome. NIF3L1 interacts with itself and with the NIF3L1 binding protein 1 (NIF3L1 BP1), which is a novel protein presumed to contain a leucine zipper domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12402R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12402R-A488
Lokale Artikelnummer::
BOSSBS-12402R-A488
Beschreibung:
RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15401R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15401R-A350
Lokale Artikelnummer::
BOSSBS-15401R-A350
Beschreibung:
H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13283R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13283R-A750
Lokale Artikelnummer::
BOSSBS-13283R-A750
Beschreibung:
GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1350R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-A488
Lokale Artikelnummer::
BOSSBS-1350R-A488
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13314R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13314R-A750
Lokale Artikelnummer::
BOSSBS-13314R-A750
Beschreibung:
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12881R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12881R-A350
Lokale Artikelnummer::
BOSSBS-12881R-A350
Beschreibung:
ABTB1 is a 478 amino acid protein localized to the cytoplasm. ABTB1 contains two ANK repeats and two BTB (POZ) domains. The BTB (POZ) domain is thought to be involved in protein-protein interactions, and may indicate a role of ABTB1 in developmental processes. It has also been suggested that ABTB1 may be a mediator of the PTEN growth-suppressive signaling pathway. ABTB1 is ubiquitously expressed in all fetal tissues, with lower levels of expression found in adult heart. ABTB1 exists as four isoforms produced by alternative splicing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1966R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1966R-A750
Lokale Artikelnummer::
BOSSBS-1966R-A750
Beschreibung:
May catalyse the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11629R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11629R-A680
Lokale Artikelnummer::
BOSSBS-11629R-A680
Beschreibung:
Olfactory receptors are G protein-coupled receptors that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction that propagates nerve impulses throughout the body, ultimately leading to transmission of the signal to the brain and the subsequent perception of smell. OR10J3 (olfactory receptor 10J3) is a 329 amino acid protein. The gene encoding OR10J3 maps to human chromosome 1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-A750
Lokale Artikelnummer::
BOSSBS-8345R-A750
Beschreibung:
FOP, is a 399 amino acid protein that localises to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterised by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-A680
Lokale Artikelnummer::
BOSSBS-8345R-A680
Beschreibung:
FOP, is a 399 amino acid protein that localises to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterised by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-A555
Lokale Artikelnummer::
BOSSBS-8345R-A555
Beschreibung:
FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11820R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11820R-A750
Lokale Artikelnummer::
BOSSBS-11820R-A750
Beschreibung:
CHURC1 is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF Signalling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11667R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11667R-A488
Lokale Artikelnummer::
BOSSBS-11667R-A488
Beschreibung:
PET112L is the human homolog of the S. cerevisiae COX assembly protein pet112, a protein that is believed to play an important role in the translation of mitochondrial genes. PET112L, also known as HSPC199 or Glu-ADT subunit B (glutamyl-tRNA(Gln) amidotransferase subunit B), is a 557 amino acid protein belonging to the gatB/gatE family of proteins (GatB subfamily) and is believed to play a role in energy metabolism. Localizing to mitochondria, PET112L is expressed in tissues such as heart and muscle, which exhibit high rates of oxidative phosphorylation. The gene encoding PET112L is overexpressed in recurrent ependymoma.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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