[4-(1H-Pyrazol-1-yl)phenyl]boronic+acid
Artikel-Nr:
(BOSSBS-12124R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12124R-A680
Lokale Artikelnummer::
BOSSBS-12124R-A680
Beschreibung:
The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients. PROT (Sodium-dependent proline transporter), also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain. PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals. Enriched in glutamatergic synaptic terminals, it is likely that PROT plays an important role in excitatory events of neurotransmission. PROT-mediated proline uptake is inhibited by compounds such as benztropine, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL). These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders.
VE:
1 * 100 µl
Artikel-Nr:
(1.08917.0100)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.08917.0100
Lokale Artikelnummer::
MERC1.08917.0100
Beschreibung:
Zirkonylchlorid Octahydrat analytisches Reagens, Supelco®
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-1232R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1232R-CY5
Lokale Artikelnummer::
BOSSBS-1232R-CY5
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1232R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1232R-CY7
Lokale Artikelnummer::
BOSSBS-1232R-CY7
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11952R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11952R-CY5
Lokale Artikelnummer::
BOSSBS-11952R-CY5
Beschreibung:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
1,10-Phenanthrolin Hydrochlorid Monohydrat 97%
Artikel-Nr:
(BOSSBS-4112R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4112R-CY5
Lokale Artikelnummer::
BOSSBS-4112R-CY5
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1232R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1232R-CY5.5
Lokale Artikelnummer::
BOSSBS-1232R-CY5.5
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3766R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3766R-CY3
Lokale Artikelnummer::
BOSSBS-3766R-CY3
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(5611-02)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR5611-02
Beschreibung:
Standardized at 25 °C against chemicals whose certification is traceable to NIST. Lot standardization value accurate to ±1 part per 1000, provided on label.
VE:
1 * 1 L
Lieferant:
MACRON AVANTOR BRAND
Beschreibung:
Salzsäure-Lösung 10% Biotech Reagent, erfüllt analytische Spezifikationen von Ph.Eur., Macron Fine Chemicals™
Artikel-Nr:
(BOSSBS-3766R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3766R
Lokale Artikelnummer::
BOSSBS-3766R
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(5621-02)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR5621-02
Beschreibung:
J.T.Baker® volumetric and analytical solutions. These solutions are suitable for use in ACS, USP and NF compendial methods and general laboratory applications.
VE:
1 * 1 L
Artikel-Nr:
(BOSSBS-11952R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11952R-CY7
Lokale Artikelnummer::
BOSSBS-11952R-CY7
Beschreibung:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11952R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11952R-HRP
Lokale Artikelnummer::
BOSSBS-11952R-HRP
Beschreibung:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11952R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11952R-A350
Lokale Artikelnummer::
BOSSBS-11952R-A350
Beschreibung:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
VE:
1 * 100 µl
Preis auf Anfrage
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