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5-Brom-2-fluor-4-nitrotoluol
Artikel-Nr:
(BOSSBS-13626R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13626R-A680
Lokale Artikelnummer::
BOSSBS-13626R-A680
Beschreibung:
Several proteins involved in regulating and executing programmed cell death have been identified in C. elegans. CED-3, a member of the ICE protease/caspase family, and CED-4, a homolog of the mammalian Apaf-1, promote apoptosis. CED-9, a homolog of the mammalian Bcl-2 protein, inhibits cell death. EGL-1 and CED-6 both function as death-promoting proteins, with CED-6 playing a role in the engulfment of apoptotic cells. CED-5 and CED-7 are C. elegans orthologs of the mammalian DOCK180 and ABC transporter proteins, respectively, and also play a role in the engulfment of dying cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7061R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7061R-A555
Lokale Artikelnummer::
BOSSBS-7061R-A555
Beschreibung:
FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4588R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4588R-A488
Lokale Artikelnummer::
BOSSBS-4588R-A488
Beschreibung:
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4587R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4587R-A680
Lokale Artikelnummer::
BOSSBS-4587R-A680
Beschreibung:
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5502R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5502R-A488
Lokale Artikelnummer::
BOSSBS-5502R-A488
Beschreibung:
MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2157R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2157R-A647
Lokale Artikelnummer::
BOSSBS-2157R-A647
Beschreibung:
Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0317R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0317R-A350
Lokale Artikelnummer::
BOSSBS-0317R-A350
Beschreibung:
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0244R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0244R-A488
Lokale Artikelnummer::
BOSSBS-0244R-A488
Beschreibung:
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11558R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11558R-A555
Lokale Artikelnummer::
BOSSBS-11558R-A555
Beschreibung:
Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0062R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0062R-A555
Lokale Artikelnummer::
BOSSBS-0062R-A555
Beschreibung:
Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2157R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2157R-A750
Lokale Artikelnummer::
BOSSBS-2157R-A750
Beschreibung:
Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7013R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7013R-A350
Lokale Artikelnummer::
BOSSBS-7013R-A350
Beschreibung:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3943R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3943R-A350
Lokale Artikelnummer::
BOSSBS-3943R-A350
Beschreibung:
G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5336R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5336R-A350
Lokale Artikelnummer::
BOSSBS-5336R-A350
Beschreibung:
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3990R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3990R-A555
Lokale Artikelnummer::
BOSSBS-3990R-A555
Beschreibung:
This gene encodes a member of the glycogenin family. Glycogenin is a glycosyltransferase that catalyzes the formation of a short glucose polymer from uridine diphosphate glucose in an autoglucosylation reaction. This reaction is followed by elongation and branching of the polymer, catalyzed by glycogen synthase and branching enzyme, to form glycogen. This gene is expressed in muscle and other tissues. Mutations in this gene result in glycogen storage disease XV. This gene has pseudogenes on chromosomes 1, 8 and 13 respectively. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6894R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6894R-A647
Lokale Artikelnummer::
BOSSBS-6894R-A647
Beschreibung:
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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