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Artikel-Nr:
(BOSSBS-8168R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8168R-A555
Lokale Artikelnummer::
BOSSBS-8168R-A555
Beschreibung:
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0439R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0439R-CY7
Lokale Artikelnummer::
BOSSBS-0439R-CY7
Beschreibung:
Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0439R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0439R-CY3
Lokale Artikelnummer::
BOSSBS-0439R-CY3
Beschreibung:
Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0647R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0647R-A350
Lokale Artikelnummer::
BOSSBS-0647R-A350
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
VE:
1 * 100 µl
Artikel-Nr:
(AX029102)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRCAX029102
Beschreibung:
Diese gebrauchsfertigen Nährmedien können überall in der Mikrobiologie eingesetzt werden. Die Medien werden aus hochwertigen Rohstoffen hergestellt. Sie werden aus ausgewählten Trocken-Grundstoffen produziert und entsprechen den verschiedensten Normen. Die Herstellung erfolgt nach den modernsten Herstellungsprozessen mit strengen Qualitätskontrollen durch qualifizierte Mikrobiologen.
VE:
1 * 10 ST
Artikel-Nr:
(BOSSBS-7697R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7697R-A555
Lokale Artikelnummer::
BOSSBS-7697R-A555
Beschreibung:
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5777R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5777R-A488
Lokale Artikelnummer::
BOSSBS-5777R-A488
Beschreibung:
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7697R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7697R-HRP
Lokale Artikelnummer::
BOSSBS-7697R-HRP
Beschreibung:
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7697R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7697R-A350
Lokale Artikelnummer::
BOSSBS-7697R-A350
Beschreibung:
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9919R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9919R-A750
Lokale Artikelnummer::
BOSSBS-9919R-A750
Beschreibung:
Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family. The genes encoding these proteins map to chromosome 11q11-q12 and 22q12.2, respectively. Transcobalamin I is a constituent of secondary granules in neutrophils, while Transcobalamin II binds cobalamin and mediates its transport into cells. These plasma proteins are expressed in various tissues and secretions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1913R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1913R-CY3
Lokale Artikelnummer::
BOSSBS-1913R-CY3
Beschreibung:
Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
Lieferant:
Biotium
Beschreibung:
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
Artikel-Nr:
(BNUM0189-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0189-50
Lokale Artikelnummer::
BTIUBNUM0189-50
Beschreibung:
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
VE:
1 * 50 µl
Lieferant:
Merck
Beschreibung:
Calciumphosphat, EMPROVE® EXPERT Ph. Eur., BP, E341 geeignet für die Verwendung als Trägerstoff, SAFC®
Artikel-Nr:
(BOSSBS-4817R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4817R-CY7
Lokale Artikelnummer::
BOSSBS-4817R-CY7
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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