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5-Chloro-1,6-naphthyridine
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5-Chloro-1,6-naphthyridine
Artikel-Nr:
(BOSSBS-4197R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4197R-A750
Lokale Artikelnummer::
BOSSBS-4197R-A750
Beschreibung:
The Sarco(endo)plasmic-reticulum (SER) regulatory protein, Phospholamban (PLB), is a small, plasma membrane-associated protein found in the SER of cardiac, smooth and slow-twitch muscle. Believed to assemble into a pentamer, PLB regulates cardiac contractility and Ca2+ affinity for cardiac SER Ca2+ ATPase (SERCA2a). Non-phosphorylated PLB associates with SERCA2a, and inhibits Ca2+ reuptake into the SER. PLB activation occurs when key Serine/Threonine residues in PLB (Ser-10, Ser-16, Thr-17) are phosphorylated by numerous effectors, which include PKC, PKA, PKG, and CaM kinase. Phosphorylation of PLB causes dissociation from SERCA2a and a subsequent increase in the rate of Ca2+ reuptake into the SER, which accelerates ventricular relaxation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11483R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11483R-A488
Lokale Artikelnummer::
BOSSBS-11483R-A488
Beschreibung:
Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin†domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. SEMA6C, also known as SEMA Y, is a transmembrane protein expressed in fetal brain and adult skeletal muscle. Three isoforms of this semaphorin exist due to alternative splicing: SEMA6C 1, SEMA6C 2 and SEMA6C 3. The extracellular domain of SEMA6C induces growth cone collapse of dorsal root ganglion and plays a role in generation or stability of entorhino-hippocampal synapses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13319R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13319R-FITC
Lokale Artikelnummer::
BOSSBS-13319R-FITC
Beschreibung:
Belonging to the glycosyltransferase 14 family, GCNT7, also known as Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, is a 430 amino acid glycosyltransferase that is localized to the Golgi apparatus. Other members of this family include GCNT1, GCNT2, GCNT3, GCNT4 and GCNT6. GCNT1 has been shown to play an important regulatory role in the biosynthesis of mucin-type O-glycans, which serve as ligands in cell adhesion. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectin proteins. Since downregulation of Selectin ligand expression has been shown to inhibit tissue infiltration, glycosyltransferase 14 family members represent potential drug targets for the treatment of inflammatory disorders and other pathologies involving Selectin proteins.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
6-Chlor-m-kresol ≥99%
Artikel-Nr:
(BLDPBD4605-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD4605-5G
Lokale Artikelnummer::
BLDPBD4605-5G
Beschreibung:
4-Chlor-3-nitrobenzylalkohol 98%
VE:
1 * 5 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Chlor-4-fluorbenzolsulfonylchlorid 97%
Artikel-Nr:
(THSARB24-16-100)
Lieferant:
THERMO SAVANT
Hersteller-Artikelnummer::
RB24-16-100
Lokale Artikelnummer::
THSARB24-16-100
Beschreibung:
Rotor block, PP, for 24 centrifuge tubes, 16×100 mm
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-13727R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13727R-CY5
Lokale Artikelnummer::
BOSSBS-13727R-CY5
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB14 (Protocadherin beta 14) is a 798 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whos genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB14) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB14 is a single-pass type I membrane protein that contains six cadherin domains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13725R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13725R-A647
Lokale Artikelnummer::
BOSSBS-13725R-A647
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated a, b and g, all of which contain multiple tandemly-arranged genes. PCDHB10 (protocadherin b10), also known as PCHB10 or PCDH-b10, is an 800 amino acid protein that is one of 16 proteins in the protocadherin b cluster. Unlike the a and g gene clusters, whose genes are spliced to downstream constant-region exons during transcription, members of the b cluster (such as PCDHB10) do not use constant-region exons to produce mRNAs. As a result, each protocadherin b gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB10 is a single-pass type I membrane protein that contains six cadherin domains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13724R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13724R-A750
Lokale Artikelnummer::
BOSSBS-13724R-A750
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB1 (Protocadherin beta 1) is an 818 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB1) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB1 is a single-pass type I membrane protein containing six cadherin domains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12069R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12069R-CY3
Lokale Artikelnummer::
BOSSBS-12069R-CY3
Beschreibung:
The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC21B (tetratricopeptide repeat domain 21B), also known as THM1, is a 1,316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family. Localizing to cytoplasm and cytoskeleton, TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction. TTC21B may also be involved in retrograde intraflagellar transport in cilia, and is encoded by a gene that maps to human chromosome 2q24.3.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR17523-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR17523-1G
Lokale Artikelnummer::
APOSOR17523-1G
Beschreibung:
5-Chlor-2-formylphenylboronsäure 95%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Chlor-2-methoxyphenylboronsäure
Artikel-Nr:
(BLDPBD236254-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD236254-250MG
Lokale Artikelnummer::
BLDPBD236254-250MG
Beschreibung:
2-Chlor-4-(trifluormethoxy)phenylboronsäure 98%
VE:
1 * 250 mg
Lieferant:
Alfa Aesar
Beschreibung:
2-Chlor-5-(trifluormethyl)phenylboronsäure 96%
Lieferant:
Alfa Aesar
Beschreibung:
4-Chlor-3-nitrotoluol 97+%
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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