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1-Butyl-3-methylimidazolium+hydrogen+sulphate
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1-Butyl-3-methylimidazolium+hydrogen+sulphate
Artikel-Nr:
(BOSSBS-0473R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0473R-FITC
Lokale Artikelnummer::
BOSSBS-0473R-FITC
Beschreibung:
Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2609R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2609R-CY7
Lokale Artikelnummer::
BOSSBS-2609R-CY7
Beschreibung:
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4216R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4216R-A555
Lokale Artikelnummer::
BOSSBS-4216R-A555
Beschreibung:
Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2948R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2948R-A350
Lokale Artikelnummer::
BOSSBS-2948R-A350
Beschreibung:
ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. It is alternatively referred to as the RNase L inhibitor as it functions to block the activity of ribonuclease L(referenced from entrez gene).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0073R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0073R-A680
Lokale Artikelnummer::
BOSSBS-0073R-A680
Beschreibung:
Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8392R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8392R-A350
Lokale Artikelnummer::
BOSSBS-8392R-A350
Beschreibung:
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation.Neuronal activity dramatically increases the concentration of cytosolic Ca2+, which then serves as a second messenger to direct diverse cellular responses. Calmodulin is a primary mediator of Ca2+ signals in the nervous system. Ric, a protein related to the Ras subfamily of small GTPases, has the ability to bind calmodulin. In addition, two Ras-like human proteins, Rin and Rit (Ric-related gene expressed in many tissues), which are 71% and 66% identical to RIC respectively, share related G2 domains with Ric. While most members of the Ras subfamily are plasma membrane-associated and generally require a C-terminal isoprenyl group to bind to the plasma membrane, Rit and Rin lack the recognition signal for C-terminal prenylation. Transiently expressed Rit and Rin are plasma membrane-localized because both proteins contain a C-terminal cluster of basic amino acids, which provides a mechanism for membrane association. Rin binds calmodulin through a C-terminal binding motif. Rit and Ric are widely expressed, whereas expression of Rin is restricted to the neuron system. In conclusion, Rit and Rin define a novel subfamily of Ras-related proteins
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9400R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9400R-HRP
Lokale Artikelnummer::
BOSSBS-9400R-HRP
Beschreibung:
Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9138R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9138R-CY7
Lokale Artikelnummer::
BOSSBS-9138R-CY7
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZSWIM3 (Zinc finger SWIM domain-containing protein 3) is a 696 amino acid protein that contains one SWIM-type zinc finger. SWIM domains are found in a variety of eukaryotic and prokaryotic proteins and are thought to be critical for certain ubiquitination reactions. The gene encoding ZSWIM3 maps to human chromosome 20, which contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11488R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11488R-CY5
Lokale Artikelnummer::
BOSSBS-11488R-CY5
Beschreibung:
Flagella and cillia are both membrane-bound projections from the cell surface that beat in distinctive patterns. Cilia are shorter and usually more profuse than flagella and contain a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane. The ciliary membranes of all cilia hold specific receptors and ion channel proteins that initiate signaling pathways that regulate motility and/or link mechanical or chemical stimuli to intracellular transduction cascades regulating differentiation, migration and cell growth during development and in adulthood. KPL2, also known as SPEF2 (sperm flagellar 2), is a 1,822 amino acid protein that contains a calponin homology domain, three nuclear localization signals, a consensus P-loop and a proline-rich region. Required for correct axoneme develoment, KPL2 is predominantly expressed in cells with cilia or flagella. Four isoforms of KPL2 exists as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6395R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6395R-A488
Lokale Artikelnummer::
BOSSBS-6395R-A488
Beschreibung:
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8250R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8250R
Lokale Artikelnummer::
BOSSBS-8250R
Beschreibung:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1531R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1531R-FITC
Lokale Artikelnummer::
BOSSBS-1531R-FITC
Beschreibung:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12142R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12142R-A647
Lokale Artikelnummer::
BOSSBS-12142R-A647
Beschreibung:
The membranes of myelinating Schwann cells are joined by tight, gap and adherens junctions, all of which are found in regions of noncompact myelin: the paranodal loops, incisures of Schmidt-Lanterman and mesaxons. Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and basolateral membranes. Pals-associated tight junction protein (PATJ), the human homolog of Drosophila Discs Lost, is differentially localized in myelinating Schwann cells. PATJ associates with Claudin-1, CRB1 (a transmembrane protein that plays a role in epithelial cell polarity and photoreceptor development), and Pals1 (a Lin-7 associated protein). The PATJ/Pals1/CRB1 complex can form a tripartite tight junction in epithelial cells crucial to their integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0560R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0560R-A750
Lokale Artikelnummer::
BOSSBS-0560R-A750
Beschreibung:
Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12559R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12559R-A750
Lokale Artikelnummer::
BOSSBS-12559R-A750
Beschreibung:
Triggers NCR3-dependent natural killer cell activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0201R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0201R-HRP
Lokale Artikelnummer::
BOSSBS-0201R-HRP
Beschreibung:
Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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