3-(Trifluormethyl)benzolsulfonamid
Lieferant:
OZ BIOSCIENCES
Beschreibung:
DMNPE-caged luciferin is a bioluminescent luciferase substrate used to measure intracellular functions since it readily crosses cell membranes. It is a D-luciferin ester analogue of luciferin.
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Methyl-2-nitrophenylboronsäurepinakolester
Artikel-Nr:
(PRSI40-574)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
40-574
Lokale Artikelnummer::
PRSI40-574
Beschreibung:
The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and would healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. The physiological role of TGF-β3 is still unknown but its expression pattern suggests a role in the regulation of certain development processes. Recombinant TGF-β3 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.Manufactured using all non-animal reagents.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI32-119)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
32-119
Lokale Artikelnummer::
PRSI32-119
Beschreibung:
BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-493)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-493
Lokale Artikelnummer::
PRSI91-493
Beschreibung:
Serine Protease Inhibitor Kazal-Type 4 (SPINK4) is a secreted protein containing one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activity. SPINK1 mutations are associated with the development of acute and chronic pancreatitis and have been detected in all forms of chronic pancreatitis. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK9 was identified in human skin. Its expression was strong in palmar epidermis, but not detectable or very low in non palmoplantar skin.
VE:
1 * 50 µG
Artikel-Nr:
(SIAL803480-50MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
803480-50MG
Lokale Artikelnummer::
SIAL803480-50MG
Beschreibung:
The PDPH is a heterobifunctional crosslinker containing sulfhydryl-reactive pyridyldithiol and carbonyl-reactive hydrazide moieties. Pyridyldithiols react with free sulfhydryls (-SH) to form disulfide bonds. Hydrazide groups react with carbonyls (aldehydes and ketones) to form stable hydrazone bonds. Aldehyde groups can be created by periodate-oxidation of sialic acid and other sugar components of glycoprotein polysaccharides. Thus, PDPH is useful for conjugating glycoproteins and sulfhydryl-containing peptides or proteins. Likewise, PDPH is useful as a sulfhydryl-addition reagent for glycoproteins and other carbohydrates; after reaction of the hydrazide to an oxidized carbohydrate, the pyridyldithiol group can be cleaved by a reducing agent to expose a sulfhydryl group. Yet another application for PDPH is to react the primary amine of the hydrazide moiety to a carboxyl group using the crosslinker EDC.
VE:
1 * 50 mg
Artikel-Nr:
(786-453)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-453
Lokale Artikelnummer::
GENO786-453
Beschreibung:
The Phosphatase Assay Kit is designed to measure the activity of phosphatases in biological samples and to screen for agonists and inhibitors of phosphatases. The Phosphatase Assay Kit uses para-nitrophenyl phosphate (pNPP), a chromogenic substrate for most phosphatases, including alkaline phosphatases, acid phosphatases, protein tyrosine phosphatases and serine/threonine phosphatases.
VE:
1 * 1 KIT
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Fluor-4-nitrophenylboronsäurepinakolester
Artikel-Nr:
(PRSI91-953)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-953
Lokale Artikelnummer::
PRSI91-953
Beschreibung:
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (Fc gamma R ) on phagocytic cells with high affinity.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-701)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-701
Lokale Artikelnummer::
PRSI33-701
Beschreibung:
It recognises a 32 kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, Galectin 13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, Galectin-13 exists as a disulfide-linked homodimer. Galectin 13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI33-663)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-663
Lokale Artikelnummer::
PRSI33-663
Beschreibung:
It recognises a 32 kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, Galectin 13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, Galectin-13 exists as a disulfide-linked homodimer. Galectin 13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI33-662)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-662
Lokale Artikelnummer::
PRSI33-662
Beschreibung:
It recognises a 32 kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, Galectin 13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, Galectin-13 exists as a disulfide-linked homodimer. Galectin 13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(EHERXA15890000TO)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
XA15890000TO
Lokale Artikelnummer::
EHERXA15890000TO
Beschreibung:
Organic Standard, Parathion-Methyl (O,O-Dimethyl-O-4-nitrophenylthiophosphat) 100 µg/ml in Toluol, Packung: Glasflasche
VE:
1 * 1 mL
Lieferant:
Thermo Scientific
Beschreibung:
6-Nitro-2,4-xylidin
Artikel-Nr:
(PRSI26-754)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-754
Lokale Artikelnummer::
PRSI26-754
Beschreibung:
ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. ENPP6 hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.
VE:
1 * 50 µG
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Nitrophenylboronsäurepinakolester
Preis auf Anfrage
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