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Dimethyl+citraconate
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Dimethyl+citraconate
Artikel-Nr:
(BOSSBS-8307R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8307R
Lokale Artikelnummer::
BOSSBS-8307R
Beschreibung:
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8248R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8248R-CY5.5
Lokale Artikelnummer::
BOSSBS-8248R-CY5.5
Beschreibung:
May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).Tissue specificity:Ubiquitous. Widely expressed in brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6456R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6456R-A647
Lokale Artikelnummer::
BOSSBS-6456R-A647
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9912R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9912R-A750
Lokale Artikelnummer::
BOSSBS-9912R-A750
Beschreibung:
HPR is a ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9912R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9912R-A680
Lokale Artikelnummer::
BOSSBS-9912R-A680
Beschreibung:
HPR is a ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8307R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8307R-A750
Lokale Artikelnummer::
BOSSBS-8307R-A750
Beschreibung:
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8248R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8248R-A750
Lokale Artikelnummer::
BOSSBS-8248R-A750
Beschreibung:
May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).Tissue specificity:Ubiquitous. Widely expressed in brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11427R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11427R-CY3
Lokale Artikelnummer::
BOSSBS-11427R-CY3
Beschreibung:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI28-917)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-917
Lokale Artikelnummer::
PRSI28-917
Beschreibung:
TSFM associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. TSFM localizes in mitochondrion.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-8248R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8248R-A555
Lokale Artikelnummer::
BOSSBS-8248R-A555
Beschreibung:
May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).Tissue specificity:Ubiquitous. Widely expressed in brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8248R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8248R-A647
Lokale Artikelnummer::
BOSSBS-8248R-A647
Beschreibung:
May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).Tissue specificity:Ubiquitous. Widely expressed in brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12121R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12121R-A488
Lokale Artikelnummer::
BOSSBS-12121R-A488
Beschreibung:
Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11860R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R-CY3
Lokale Artikelnummer::
BOSSBS-11860R-CY3
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11427R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11427R-A350
Lokale Artikelnummer::
BOSSBS-11427R-A350
Beschreibung:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11427R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11427R-HRP
Lokale Artikelnummer::
BOSSBS-11427R-HRP
Beschreibung:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11860R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R-A350
Lokale Artikelnummer::
BOSSBS-11860R-A350
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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