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Ethyl-2-ethoxybenzoate
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Ethyl-2-ethoxybenzoate
Artikel-Nr:
(BOSSBS-12248R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R-CY5
Lokale Artikelnummer::
BOSSBS-12248R-CY5
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12311R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12311R-A750
Lokale Artikelnummer::
BOSSBS-12311R-A750
Beschreibung:
The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeats and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12311R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12311R-A680
Lokale Artikelnummer::
BOSSBS-12311R-A680
Beschreibung:
The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeats and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.
VE:
1 * 100 µl
Artikel-Nr:
(PROOICRS0403)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
ICRS0403
Lokale Artikelnummer::
PROOICRS0403
Beschreibung:
6-Propyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinon
VE:
1 * 100 mg
Artikel-Nr:
(SIAL679119-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
679119-5G
Lokale Artikelnummer::
SIAL679119-5G
Beschreibung:
7-Fluorisatin, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(BRND144520)
Lieferant:
Brand
Hersteller-Artikelnummer::
144520
Lokale Artikelnummer::
BRND144520
Beschreibung:
Boro 3.3.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-11604R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11604R-A555
Lokale Artikelnummer::
BOSSBS-11604R-A555
Beschreibung:
Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12248R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R-A647
Lokale Artikelnummer::
BOSSBS-12248R-A647
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12248R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R-A488
Lokale Artikelnummer::
BOSSBS-12248R-A488
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Artikel-Nr:
(BLEG124627)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
124627
Lokale Artikelnummer::
BLEG124627
Beschreibung:
Anti-CD40 Rat Monoclonal Antibody [clone: 3/23] (Ultra-LEAF™)
VE:
1 * 100 µG
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BLEG124639)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
124639
Lokale Artikelnummer::
BLEG124639
Beschreibung:
Anti-CD40 Rat Monoclonal Antibody [clone:3/23](TotalSeq™-B0903)
VE:
1 * 10 µG
This is a MarketSource item. Additional charges may apply
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-HAVCR2 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: RMT3-23]
Lieferant:
Alfa Aesar
Beschreibung:
Felodipin
Artikel-Nr:
(BOSSBS-11805R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11805R-A750
Lokale Artikelnummer::
BOSSBS-11805R-A750
Beschreibung:
AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer. Alternative splicing generates the ATBF1-A and ATBF1-B. While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains. Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs. The N-terminal extension unique to ATBF1-A has transcriptional repressor activity. In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element. Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity. ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs. ATBF1 is highly expressed in spleen and brain tissues. The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11604R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11604R
Lokale Artikelnummer::
BOSSBS-11604R
Beschreibung:
Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12311R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12311R-CY3
Lokale Artikelnummer::
BOSSBS-12311R-CY3
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeasts and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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