2-(3-(Trifluoromethyl)phenyl)propanoic+acid
Artikel-Nr:
(BOSSBS-11153R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11153R-A488
Lokale Artikelnummer::
BOSSBS-11153R-A488
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11480R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11480R-HRP
Lokale Artikelnummer::
BOSSBS-11480R-HRP
Beschreibung:
Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin†domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA3E is a secreted semaphorin with 775 amino acids. Mutations in the SEMA3E gene are associated with CHARGE syndrome, a disorder characterized by cranial nerve dysfunction, coloboma of the eye, choanal atresia, inner and external ear abnormalities, cardiac anomalies, genitourinary abnormalities, and growth retardation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11153R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11153R-A350
Lokale Artikelnummer::
BOSSBS-11153R-A350
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11592R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11592R-CY3
Lokale Artikelnummer::
BOSSBS-11592R-CY3
Beschreibung:
Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstré°‰ syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11592R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11592R
Lokale Artikelnummer::
BOSSBS-11592R
Beschreibung:
Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstré°‰ syndrome.
VE:
1 * 100 µl
Lieferant:
VACUUBRAND
Beschreibung:
Dichtungssatz für MZ 8/MD 8/ME 16
Artikel-Nr:
(PRSI4995P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4995P
Lokale Artikelnummer::
PRSI4995P
Beschreibung:
IL-16 peptide is used for blocking the activity of IL-16 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(USBI041807-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041807-BIOTIN
Lokale Artikelnummer::
USBI041807-BIOTIN
Beschreibung:
Anti-SLC16A8 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Lieferant:
UVP ULTRA VIOLET PRODUCTS
Beschreibung:
Ersatzfilter, Für: EL Serie Lampen UVM-16 und UVS-16
Artikel-Nr:
(BTOL620242)
Lieferant:
BIOTOOL
Hersteller-Artikelnummer::
620242
Lokale Artikelnummer::
BTOL620242
Beschreibung:
Innenbehälter, 16 l für PC20B
VE:
1 * 1 ST
Lieferant:
Cytiva
Beschreibung:
Anschluss 1/16" außen/Luer innen, für HiScale™ 16 und 26
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interleukin 16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin 2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).
Artikel-Nr:
(BAIL19061)
Lieferant:
BAILLY
Hersteller-Artikelnummer::
19061
Lokale Artikelnummer::
BAIL19061
Beschreibung:
For 6 hemolysis tubes (Ø 16 mm).
VE:
1 * 1 ST
Lieferant:
Biotium
Beschreibung:
This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
Lieferant:
Biotium
Beschreibung:
This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
Artikel-Nr:
(BNUM0675-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0675-50
Lokale Artikelnummer::
BTIUBNUM0675-50
Beschreibung:
This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
VE:
1 * 50 µl
Preis auf Anfrage
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