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Potassium+trifluoro(hex-1-yn-1-yl)borate
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Potassium+trifluoro(hex-1-yn-1-yl)borate
Artikel-Nr:
(BOSSBS-5962R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5962R-A488
Lokale Artikelnummer::
BOSSBS-5962R-A488
Beschreibung:
Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5962R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5962R-CY5
Lokale Artikelnummer::
BOSSBS-5962R-CY5
Beschreibung:
Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR8707-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR8707-1G
Lokale Artikelnummer::
APOSOR8707-1G
Beschreibung:
[4-(4-Methylhomopiperazin-1-yl)phenyl]methanol 97%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-12422R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12422R-A555
Lokale Artikelnummer::
BOSSBS-12422R-A555
Beschreibung:
14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms, denoted 14-3-3 b, g, e, z, h, q and s, comprise this family of signaling intermediates. 14-3-3 s, also known as SFN, stratifin, HME1 or YWHAS, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways. Expressed predominately in stratified squamous keratinising epithelium, 14-3-3 s is able to bind and modify the activity of a large number of proteins, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif. When bound to Keratin 17, for example, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth. 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, thus controlling mitotic translation. In response to tumor growth, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression. Multiple isoforms of 14-3-3 s exist due to alternative splicing events.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,2,4,5-Tetrafluor-3,6-dimethylbenzol 98%
Lieferant:
Alfa Aesar
Beschreibung:
Dexamethason ≥98%
Artikel-Nr:
(HECH44001012)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
44001012
Lokale Artikelnummer::
HECH44001012
Beschreibung:
Soda-Kalkglas
VE:
1 * 1 ST
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(Furo[3,2-c]pyridin-4-yl)homopiperazine
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Oosporein
Artikel-Nr:
(BOSSBS-9615R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R-HRP
Lokale Artikelnummer::
BOSSBS-9615R-HRP
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(SCOR1028140)
Lieferant:
Schott AG
Hersteller-Artikelnummer::
1028140
Lokale Artikelnummer::
SCOR1028140
Beschreibung:
Made of AR®-Glas.
VE:
1 * 13,8 kg
Artikel-Nr:
(BOSSBS-8226R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8226R-CY5
Lokale Artikelnummer::
BOSSBS-8226R-CY5
Beschreibung:
FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5% of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer’s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
α,α'-Dibrom-p-xylol ≥97%
Lieferant:
Alfa Aesar
Beschreibung:
2,5-Dibromtoluol ≥98%
Lieferant:
Alfa Aesar
Beschreibung:
2,3-Dimethoxy-5-methyl-p-benzochinon ≥98%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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