Artikel-Nr:
(EHERC13060500)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C13060500
Lokale Artikelnummer::
EHERC13060500
Beschreibung:
Ethyllaurat
VE:
1 * 0,25 g
Artikel-Nr:
(ACRO467841000)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
467841000
Lokale Artikelnummer::
ACRO467841000
Beschreibung:
Chemical probes can be used to help establish the
relationship between a molecular target and the broader biological consequences of modulating that target in cells or organisms.
VE:
1 * 100 mg
Artikel-Nr:
(EHERC15084600)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C15084600
Lokale Artikelnummer::
EHERC15084600
Beschreibung:
tert-Butylmethylether
VE:
1 * 5 mL
Artikel-Nr:
(CHMPMB00009.250)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
MB00009.250
Lokale Artikelnummer::
CHMPMB00009.250
Beschreibung:
5-Iod-o-toluidin
VE:
1 * 250 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
N-Fmoc-L-alanine 95% (durch HPLC), Sigma-Aldrich®
Lieferant:
COMBI-BLOCKS
Beschreibung:
3-(3-Chlorbenzyloxy)phenylboronsäure
Lieferant:
COMBI-BLOCKS
Beschreibung:
tert-Butyl-4-brombutyrat
Artikel-Nr:
(SIAL154180-10G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
154180-10G
Lokale Artikelnummer::
SIAL154180-10G
Beschreibung:
2-(4-Methoxyphenyl)ethanol, Sigma-Aldrich®
VE:
1 * 10 g
Artikel-Nr:
(470190010.)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
470190010
Lokale Artikelnummer::
ACRO470190010
Beschreibung:
Levosimendan 98%
VE:
1 * 1 g
New Product
Artikel-Nr:
(EHERC10265900)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C10265900
Lokale Artikelnummer::
EHERC10265900
Beschreibung:
p-Anissäure
VE:
1 * 0,25 g
Artikel-Nr:
(BOSSBS-4211R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4211R-CY3
Lokale Artikelnummer::
BOSSBS-4211R-CY3
Beschreibung:
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, H2AFY and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4. The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4211R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4211R-A750
Lokale Artikelnummer::
BOSSBS-4211R-A750
Beschreibung:
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, H2AFY and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4. The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4211R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4211R-A647
Lokale Artikelnummer::
BOSSBS-4211R-A647
Beschreibung:
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, H2AFY and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4. The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539).
VE:
1 * 100 µl
Artikel-Nr:
(178385-1)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
178385-1
Lokale Artikelnummer::
CALB178385-1
Beschreibung:
4'-Hydroxy-3'-methoxyacetophenon, Millipore®
VE:
1 * 1 g
Artikel-Nr:
(SIALD4693-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
D4693-1G
Lokale Artikelnummer::
SIALD4693-1G
Beschreibung:
The enzyme can be initially dissolved in 50 mM Hepes/KOH pH 7,4, 150 mM NaCl at 10 mg/ml.
VE:
1 * 1 g
Lieferant:
FLUOROCHEM
Beschreibung:
(3,5-Bis(trifluormethyl)phenyl)essigsäure
Preis auf Anfrage
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