3,3'-Dimethylbenzidin+Dihydrochorid
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(3-Chlor-5-(trifluormethyl)-2-pyridinyl)tetrahydro-4(1H)-pyridinon
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-(Morpholinomethyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-(Bromoacetyl)-2,3-dihydro-1,4-benzodioxine
Artikel-Nr:
(BLDPBD160152-10G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD160152-10G
Lokale Artikelnummer::
BLDPBD160152-10G
Beschreibung:
7-Hydroxy-1-indanone 97%
VE:
1 * 10 g
Artikel-Nr:
(BOSSBS-9616R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9616R-A488
Lokale Artikelnummer::
BOSSBS-9616R-A488
Beschreibung:
Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR110679-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR110679-1G
Lokale Artikelnummer::
APOSOR110679-1G
Beschreibung:
4-(3-Bromophenyl)-2-butanone
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-11236R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11236R-CY5
Lokale Artikelnummer::
BOSSBS-11236R-CY5
Beschreibung:
During vertebrate embryogenesis, a left right axis is established. Secreted growth factors of the TGF beta family, including gene products derived from nodal, lefty 1 and lefty 2, play crucial roles in establishing left right asymmetries. TGF beta (Transforming growth factor beta) is a pleiotropic cytokine that regulates growth and differentiation of diverse types of cells. TGF beta actions are directed by ligand induced activation of TGF beta receptors. Complexes formed move into the nucleus, where they act as components of a transcriptional complex. Lefty, a novel member of the TGF beta superfamily, inhibits TGF beta signaling. Lefty acts to inhibit phosphorylation of Smad2 following activation of the TGF beta receptor. Lefty also inhibits events downstream from R Smad phosphorylation. Lefty provides a repressed state of TGF beta responsive genes. The Lefty family is comprised of Lefty 1 and Lefty 2 in mouse, and Lefty A and Lefty B in humans. Members of the TGF beta superfamily require processing for their activation. Cleavage is therefore an essential step for Lefty activation. Lefty is synthesized as a large inactive precursor (41 Kda) that must be endoproteolytically processed to release the bioactive polypeptide (28 kDa and 34 kDa forms). The 28kDa form induces MAPK activity.
VE:
1 * 100 µl
Artikel-Nr:
(74886-6EA-F)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
74886-6EA-F
Lokale Artikelnummer::
SUPL74886-6EA-F
Beschreibung:
Dilute contents of one ampule (~0.3 M) to 1 L with HPLC grade water to obtain a 0.005 M eluent solution.
VE:
1 * 6 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
Riboflavin-5'-phosphat Natriumsalz Dihydrat, Sigma-Aldrich®
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Hydroxy-1-indanon 97%
Artikel-Nr:
(BOSSBS-11489R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11489R-FITC
Lokale Artikelnummer::
BOSSBS-11489R-FITC
Beschreibung:
TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11458R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11458R-CY5
Lokale Artikelnummer::
BOSSBS-11458R-CY5
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-CY5
Lokale Artikelnummer::
BOSSBS-11726R-CY5
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R
Lokale Artikelnummer::
BOSSBS-11726R
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11489R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11489R-A350
Lokale Artikelnummer::
BOSSBS-11489R-A350
Beschreibung:
TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13084R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13084R-A555
Lokale Artikelnummer::
BOSSBS-13084R-A555
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Preis auf Anfrage
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